TARINA FE 1/20 Rx
Generic Name and Formulations:
Norethindrone acetate 1mg, ethinyl estradiol 0.02mg (21 tabs); inert+ (7 tabs); +contains ferrous fumarate 75mg.
Indications for TARINA FE 1/20:
1 tab daily for 28 days; repeat. Take at the same time daily with a meal or at bedtime. Use Day 1 or Sunday start for 1st cycle; use backup method for first 7 days.
Pre-menarchal: not applicable.
Thrombophlebitis or thromboembolic disorders. History of DVT. Cerebral vascular or coronary artery disease. Known or suspected breast carcinoma, endometrial carcinoma or other estrogen-dependent neoplasia. Undiagnosed abnormal genital bleeding. Cholestatic jaundice of pregnancy or jaundice with prior pill use. Hepatic adenoma or carcinoma. Pregnancy (Cat.X). Concomitant ombitasvir/paritaprevir/ritonavir, with or without dasabuvir.
Cigarette smoking increases risk of serious cardiovascular events.
Increased risk of cardiovascular events (eg, MI, stroke, DVT, VTE) esp. smokers >35 years of age. Discontinue if thrombotic event, unexplained visual changes, persistently elevated BP, or jaundice occurs, and at least 4 weeks before through 2 weeks after surgery associated with increased risk of thromboembolism, and during and after prolonged immobilization. Cardio- or cerebrovascular diseases. Increased risk of breast cancer or hepatic neoplasia. Hypertriglyceridemia. Obesity. Diabetes. Prediabetes. Gallbladder disease. Depression. Evaluate significant changes in headaches, abnormal vaginal bleeding, amenorrhea. Conditions aggravated by fluid retention; monitor. Do regular complete physical exams (eg, Pap smear, mammogram, BP). May need barrier contraception with Sunday starts or postpartum use (see full labeling). Postmenopausal women or nursing mothers: not recommended.
Progestin + estrogen.
See Contraindications. ALT elevations with HCV regimen ombitasvir/paritaprevir/ritonavir, with or without dasabuvir; discontinue Tarina Fe prior to starting HCV regimen and restart 2wks after completion. May be antagonized by rifampin, phenobarbital, phenytoin, carbamazepine, troglitazone, ampicillin, tetracycline, griseofulvin, phenylbutazone, others. May be potentiated by atorvastatin, ascorbic acid, acetaminophen. May antagonize acetaminophen, temazepam, salicylic acid, morphine, clofibric acid. May potentiate cyclosporine, prednisolone, theophylline. May affect lab tests (eg, coagulation factors, triglycerides, lipids, glucose tolerance, binding proteins, hormone binding globulins, serum folate).
Hypertension, nausea, vomiting, breakthrough bleeding, change in menstrual flow, amenorrhea, temporary infertility after discontinuation, edema, melasma, headache, intolerance to contact lenses; serious thromboembolic events, liver disease.
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