In order to evaluate the relationship of sleep disturbance to the antidepressant effects of esketamine, 2 double-blind, 4-week studies randomized adults with treatment-resistant depression (TRD) to placebo or esketamine nasal spray.
The researchers’ primary goal was to summarize existing evidence about daily associations between sleep and physical activity outcomes at inter- and intra-individual levels in adults.
With the use of sleep medication increasing, little is known about the long-term benefits of these medications. The researchers compared reductions in sleep difficulties across a large cohort of women who used and did not use prescription sleep medication.
Middle-aged women who initiate sleep medications do not have significant improvement in their sleep disturbance compared with those who do not initiate medications.
Sodium oxybate treatment may be associated with weight reduction and stabilization in children with type 1 narcolepsy.
In order to assess the efficacy and safety of JZP-258, a lower sodium alternative product to sodium oxybate, study authors designed a double-blind, placebo-controlled, randomized withdrawal, multicenter study with an open-label safety extension.
Individuals most at risk for neurobehavioral performance impairment during sleep deprivation can be accurately identified by a visual psychomotor vigilance task.
In patients with suspected or confirmed OSA, clinically significant erythrocytosis appears uncommon.
Long-term abstinence after cocaine dependence was shown to be associated with improved sleep quality after an initial worsening period.
OSA is associated with sight-threatening diabetic retinopathy and with progression to pre-/proliferative DR for patients with type 2 diabetes.
