Schizophrenia, Bipolar Disorder, and the Psychosis Continuum
Awareness of differences between psychosis in schizophrenia and bipolar disorder and varying presentations in patients can assist providers with diagnosis and treatment.
Schizophrenia
Public Impressions on Likelihood of Violence in People With Mental Illness
By 2018, more than 60 percent perceived those with schizophrenia as dangerous; many support coercive treatment.
Novel Trace Amine Receptor Associated With Significant Antipsychotic Effects in Schizophrenia
Researchers evaluated the efficacy and safety of trace amine associated receptor-1 agonist SEP-363856 in patients with schizophrenia.
Transdermal Asenapine: A Promising Potential Treatment Option for Adults With Schizophrenia
If approved, HP-3070 would be the first transdermal antipsychotic available in the United States, and would provide a novel, safe, and efficacious treatment delivery system for adult patients with schizophrenia.
ALKS 3831 May Provide Long-Term Benefits for Acute Schizophrenia
Over the course of 52 weeks, a combination of olanzapine and samidorphan was associated with minimal weight gain, tolerable adverse events, and durable antipsychotic effects in patients with schizophrenia.
Relapse More Likely With Antipsychotic Switch in Schizophrenia, Bipolar Disorder, or MDD
Patients with schizophrenia or a mood disorder who switched antipsychotic treatment had an increased likelihood for relapse, healthcare resource utilization, and extrapyramidal symptoms.
Enhanced Cortical Androgen Action Noted in Bipolar Disorder
Patients with bipolar disorder may experience elevated cortical androgen activity compared with individuals without bipolar disorder.
Clinical Utility of Delay Discounting in Psychiatric Disorders
Delay discounting may be considered a transdiagnostic process across many psychiatric disorders, such as bipolar disorder and borderline personality disorder.
Childhood Adversity Linked to Cognitive Impairment in Schizophrenia
People with schizophrenia and cognitive impairment reported significant childhood adversity, especially the lack of parental involvement and family hardships.
Better Outcomes in Pediatric-Onset vs Adult-Onset Bipolar Disorder
Individuals with pediatric-onset bipolar disorder fare better than individuals diagnosed at a later age with the disorder, and bipolar disorder in general is associated with better outcomes than schizophrenia.
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