The researchers concluded that the correlation between interregional cortical thinning during maturation and expression patterns of genes associated with multiple psychiatric disorders suggested a common molecular process.
Patients with schizophrenia and a history of catatonia had greater deficits in the cognitive domains of immediate memory, verbal fluency, and processing speed compared to patients with schizophrenia alone.
To learn more about SEP-363856 as a novel treatment for schizophrenia, we spoke with Kenneth Koblan, PhD, and John Krystal, MD.
The state has increased telehealth assessments and treatments for patients with psychiatric and addictive disorders through state Medicaid, third party, and federal Medicare and HIPAA waivers.
Patients with bipolar disorder experienced significant reductions in sleep efficiency, which was not the case in patients with schizophrenia, although effect sizes for bipolar disorder were smaller overall.
In patients with schizophrenia, cannabis use may be linked to elevated risk of all-cause mortality but decreased risk of mortality from digestive organ diseases.
Given the increased risk for opioid-related problems among patients with psychiatric diagnoses, the investigators advised a more cautious approach to prescribing that integrates expertise from mental health clinicians.
Among patients with schizophrenia, long-term antipsychotic use does not appear to increase severe physical morbidity or somatic hospitalization, and mortality is lower for antipsychotic use compared with no use.
The findings suggest that factors such as antipsychotic treatment, diet, or lifestyle may contribute to weight gain in patients with long-term disease.
Researchers conducted a case-control study to examine the associations between polygenic risk scores for schizophrenia and other mental disorders with the development of cannabis use disorder.
