Nasal Spray Option May Improve Antipsychotic Drug
Delivery of antipsychotic drugs via the nasal cavity circumvents multiple barriers for reaching the brain but requires a vehicle with specific properties to be effective.
Schizophrenia And Psychoses
Medication May Not Be the Sole Reason for Sleepiness in Psychosis Patients
The researchers used various questionnaires to assess quality of life, psychiatric symptoms, sleepiness, and fatigue in those with psychosis.
Black and Hispanic Patients Have Significant Barriers to Accessing Psychological Care Despite Continuously Held Private Insurance
While racial and ethnic disparities in health care, including in behavioral health disorders, are known, disparities during first-episode psychosis have not been fully explored.
Machine Learning Predicts Psychosis in High-Risk Patients
The study authors evaluated whether psychosis transition can be predicted in patients with clinical high-risk or recent-onset depression using multimodal machine learning that integrates clinical and neurocognitive data, structural magnetic resonance imaging, and polygenic risk scores for schizophrenia.
Physical Activity Might Not Reduce Schizophrenia Risk
Physical activity might not protect against schizophrenia risk.
Characterizing the Effect of CYP2C19/CYP2D6 Genotype on Plasma Drug Exposure to Antidepressant, Antipsychotic Medications
The researchers of this study sought to quantify the difference in antipsychotic and antidepressant exposure among patients with genetically associated CYP2C19 and CYP2D6 poor (PM), intermediate (IM), and normal (NM) metabolizers.
Hallucination Symptom of Schizophrenia Associated With Heart Rate-Adjusted Interoceptive Accuracy
The researchers of this study suggest that interoception in schizophrenia could be a new therapeutic target.
Smartphone Data Helps Measure Verbal Hallucinations
In this study participants used a multi-modal smartphone data collection system to report on their AVH experiences and co-occurring psychological states multiple times daily, over 30 days. At the same time, smartphone sensors recorded their physical activity, geolocation, and calling and texting behavior.
What Role Might the G Protein-Coupled Estrogen Receptor 1 Have in Treating Schizophrenia?
Researchers conducted a literature review of the research published through July 2020 on the estrogen receptor’s potential as a therapeutic target for treatment of schizophrenia.
Brain Structural Changes May Indicate Genetic Liability for Schizophrenia
Specific structural changes in the brain may indicate genetic risk for schizophrenia and suggest different neurobiological pathways to the disorder.
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