Ongoing Exposure to Stressors Harms Health
Chronic exposure to stressors leads to an erosion of health, as measured by allostatic load, which is particularly severe among foreign-born Black and Latino individuals.
PTSD Trauma And Stressor-related
Activation of Certain Brain Regions Correlated with Subsequent Response to CBT for PTSD
While trauma-focused cognitive-behavioral therapy is an important component of evidence-based treatment for posttraumatic stress disorder, the efficacy of treatment can vary between individuals. It is thought that some of this variability is derived from interindividual differences in the brain’s intrinsic response to trauma-related stimuli and in activity of executive functional regions. The authors of this study sought to characterize these differences using a functional MRI in patients about to undergo CBT for PTSD.
Long-Term Exposure to a Mediterranean Diet Positively Alters Stress Response and Promotes Healthy Aging
There is a need for better understanding of factors that influence stress response as little progress has been made to effectively reduce stress responses. Evidence suggests that diet may be a factor in modifying the effects of stress.
Overactivating the Brain Causes Elevated Arousal and Threat Response
By combining targeted intracerebral microinfusions with cardiovascular and behavioral monitoring in marmosets, we show that overactivation of sgACC/25 reduces vagal tone and heart rate variability, alters cortisol dynamics during stress and heightens reactivity to proximal and distal threat.
Increased Time in Rapid Eye Movement Sleep Following a Traumatic Event May Offset Symptoms of Fear
Given the interactions of sleep with learning and memory, researchers hypothesized that increasing sleep duration following trauma exposure would restore overall function and improve trauma-induced fear-associated memory dysfunction.
Role of Amygdala Inhibitory Neurons in Conditioned Threat Response, Emotional Memories
This study provides evidence that the disruption of protein synthesis in discrete inhibitory neuron subpopulations in the centrolateral amygdala impairs associative memories related to threat and safety, which may contribute to maladaptive behavior in memory disorders such as PTSD.
High Prevalence of Maladaptive Daydreaming Among Patients With Dissociative Disorders
Determining the frequency of maladaptive daydreaming in a sample of psychiatric inpatients with high levels of dissociation.
Psychiatric Comorbidities May Raise Risk for Sedative Use Disorder in Patients with Opioid Use Disorder
Over half of the sample attained opioids through their own prescription, and 47.2% of patients with co-occurring sedative use disorder attained sedatives by prescription.
Emotion Dysregulation Mediates the Effects of Trauma on Depression, Positive Symptoms in Psychosis
Maladaptive cognitive emotion regulation and global emotion dysregulation emerged as mediators of the effects of trauma on depressive and positive symptoms in early nonaffective psychosis.
In Older Adults with PTSD, Brief ISI May Be a Clinically Pragmatic Option
In a cohort study of older veterans with combat or military related PTSD, the brief ISI was significantly correlated with results from the original yet longer ISI.
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