Sertraline and adjunctive olanzapine reduced the risk for relapse in patients with psychotic depression; however, patients experienced such adverse effects of olanzapine as weight gain.
When compared with native populations and non-refugee migrants in a host country, refugees have a particular risk of developing non-affective psychosis.
The pattern of increasing psychotic-like experiences, minority status, trauma, and family divorce were predictive of emergent mental disorders in a cohort of Chinese youth.
A phase 3 trial evaluating pimavanserin (Acadia) for the treatment of dementia-related psychosis has been stopped early due to positive findings in a planned interim efficacy analysis.
Although the number of young people with attention-deficit/hyperactivity disorder (ADHD) who are treated with antipsychotic drugs is low, many antipsychotic prescriptions do not appear to be clinically warranted.
Variables that significantly contributed to functional outcomes in bipolar disorder included a history of psychotic symptoms followed by depression and executive functioning and verbal memory.
Social problems were related to subclinical delusions but not subclinical hallucinations in a representative adolescent population.
Typical antipsychotic use is not associated with an increased risk for strokes compared with atypical antipsychotic use in a non-elderly population and patients without dementia.
An increasing number of adolescents and young adults use cannabis for recreational or medicinal purposes, unaware that potential adverse effects include psychosis.
A lack of belief in the value of medication and the number of previous hospitalizations also predict hospitalization in first-episode psychosis.
