Weight Changes with Lower-Sodium Oxybate in Idiopathic Hypersomnia
Weight loss for patients with narcolepsy has been linked with sodium oxybate (SXB) treatment. Researchers sought to investigate weight changes associated with LBX.
Narcolepsy
Narcolepsy, Sodium Intake, and Heart Health: This Expert Explains It All
Richard K. Bogan, MD, discusses the importance of lowering sodium intake and improving heart health for patients with narcolepsy.
Meta-Analysis: Patients with Narcolepsy Have Poorer Quality Nighttime Sleep, Polysomnography Shows
The researchers of this study conducted a systematic review of literature on polysomnographic differences between patients with narcolepsy and healthy controls.
Effects of Sodium Oxybate on Weight in Children with Type 1 Narcolepsy
Sodium oxybate treatment may be associated with weight reduction and stabilization in children with type 1 narcolepsy.
Coronavirus Pandemic Impacts Sleep Pattern of Patients With Narcolepsy
A recent study showed that COVID-19 quarantining has led to people going to bed later, getting up earlier, and getting lower quality sleep, the impact of the COVID-19 pandemic on patients with narcolepsy has not yet been determined.
Study Considerations for Efficacy, Safety of JZP-258 for Idiopathic Hypersomnia
In order to assess the efficacy and safety of JZP-258, a lower sodium alternative product to sodium oxybate, study authors designed a double-blind, placebo-controlled, randomized withdrawal, multicenter study with an open-label safety extension.
Solriamfetol Improves Several Quality of Life Markers in People With Narcolepsy
Solriamfetol offers short-term improvements in functional status, health-related quality of life, and work productivity in people with narcolepsy.
Excessive Sleepiness Worsens in Parkinson’s As Disease Progresses
Researchers find narcolepsy symptoms the most severe in patients taking dopamine agonists, so clinicians should be cautious in using them.
Drug Improves Excessive Sleepiness in Narcolepsy With or Without Cataplexy
Sodium oxybate, alone or in combination with modafinil, improved excessive sleepiness in patients with narcolepsy both with and without cataplexy.
Novel Narcolepsy Drug Demonstrates Improvement in Daytime Sleepiness
Post-hoc analysis of Phase IIb trial finds both clinician and patient-reported improvements in disease status with JZP-110.
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