Bipolar Disorder Linked to Increased Risk for Major Adverse Cardiac Events
A team of researchers investigated the relationship between bipolar disorder and major adverse cardiac events.
Major Depressive Disorder
Severity of Major Depressive Disorder Influences Direct and Indirect Healthcare Costs
Investigators examined healthcare costs of adult patients with mild, moderate, moderately severe, and severe major depressive disorder and compare them with a control group representative of the general population.
Patient Priorities for Medication Management Strategies for Serious Mental Illnesses
Researchers conducted web-based focus groups to better understand patient preferences for medication management of a serious mental illness.
Adjunctive Bexpiprazole May Help Individuals With Symptoms of Anxious Distress
A team of investigators sought to assess the efficacy of brexpiprazole as an adjunct to antidepressant treatment in patients with major depressive disorder and anxious distress.
Zuranolone Not Associated With Impaired Sexual Function in Depression
Investigators sought to assess the effect of zuranolone vs placebo on the sexual functioning of adults with major depressive disorder.
Pimavanserin Effective for Depression in Parkinson Disease, Major Depressive Disorder
Researchers conducted an 8-week, open-label, single-arm study and a subsequent 2-stage, sequential, parallel comparison study to assess the use of pimavanserin among patients with Parkinson disease and major depressive disorder.
Cognition Kit DSST App Validated for Measuring Major Depressive Disorder
Researchers conducted a study to evaluate the validity of, and satisfaction with, the Cognition KIT DSST mobile app in patients with major depressive disorder.
Screening Tool Effective for Identifying Bipolar I Disorder During a Depressive Episode
Investigators conducted a comprehensive literature search to identify key characteristics that best differentiate between bipolar I disorder and major depressive disorder.
Spravato Approved for MDD With Acute Suicidal Ideation or Behavior
The approval was based on the ASPIRE I and II trials that compared the efficacy and safety of esketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, to placebo in 449 adults with moderate to severe MDD who had active suicidal ideation and intent.
Diagnostic Considerations in Major Depressive Disorder With Psychotic Features
Investigators sought to determine the prevalence of psychotic features in patients with major depressive disorder.
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