Between 1991 and 2011, there were improvements in disability-free life expectancy (DFLE) for older people with a broad number of long-term conditions (LTCs), except for cognitive impairment.
In this drug repurposing network analysis and retrospective case-control study, an Alzheimer disease (AD) endophenotype model was made using data from large-scale amyloid or tauopathy genome-wide association studies. Drugs approved by the United States Food and Drug Administration were evaluated for their effect on the AD endophenotype.
When cognitive changes as people age are not identified in a timely manner, this delays diagnosis as well as treatment. In a study, researchers compared the scores for 665 patients of a self-administered cognitive test vs a non-self-administered cognitive test to detect dementia.
This study points to potential differences in how social isolation and loneliness may affect — and reflect — health and wellbeing for older adults.
The majority of older US adults commonly experience ageism in their daily lives.
In 2016, an estimated 5.4 million US adults have Alzheimer disease.
The extent or severity of physical ailments and functional impairment needs to be carefully examined in order to successfully prevent suicide in late life.
Dementia risk was particularly elevated in patients with depression who had higher scores on cognitive tests at baseline.
To date, there are no validated biomarkers to independently assess Parkinson Disease diagnosis and prognosis, or to measure disease severity.
Interventions are needed to enhance adherence to prescribed medications, especially in older adults experiencing new episodes of depression.
