CBT for treatment-resistant depression

Activation of Certain Brain Regions Correlated with Subsequent Response to CBT for PTSD

While trauma-focused cognitive-behavioral therapy is an important component of evidence-based treatment for posttraumatic stress disorder, the efficacy of treatment can vary between individuals. It is thought that some of this variability is derived from interindividual differences in the brain’s intrinsic response to trauma-related stimuli and in activity of executive functional regions. The authors of this study sought to characterize these differences using a functional MRI in patients about to undergo CBT for PTSD.

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