Chronic Rhinosinusitis Linked to Depression, Anxiety
Chronic rhinosinusitis (CRS) is associated with incidence of depression and anxiety.
Depressive Disorder
Certain Opioids Less Effective With SSRI Antidepressants
Certain opioids are less effective for postoperative pain in patients taking selective serotonin reuptake inhibitor antidepressants.
FDA Committees Vote on Esketamine Nasal Spray for Treatment-Resistant Depression
If approved by the FDA, an esketamine nasal spray would provide a new mechanism of action for treating treatment-resistant depression.
Heart Rate Variability May Predict Therapeutic Response in Major Depressive Disorder, Panic Disorder
Heart rate variability factors may predict therapeutic response in patients with major depressive disorder and panic disorder.
Family History of Depression Associated With Worse Cognition in First-Degree Relatives
General impairment in cognition is a feature of first-degree relatives of family members with major depressive disorder.
Effects of Physical Activity on Major Depressive Disorder Risk
Findings validate a potential protective relationship between physical activity and depression and indicate the need for objective measurement of physical activity in mental health studies.
USPSTF: New Recommendations for Preventing Perinatal Depression
The US Preventive Services Task Force concluded that providing or referring pregnant or postpartum women to counseling has a moderate net benefit in preventing perinatal depression.
FDA Rejects Opioid System Modulator NDA for Depression Treatment
The FDA has issued a Complete Response Letter to Alkermes regarding the New Drug Application for ALKS 5461, an investigational adjunctive treatment for major depressive disorder.
Physical Activity May Be Protective Against Cognitive Decline in Older Adults With Depression
Participating in physical activity for 150 min/wk at moderate-to-vigorous intensity may protect older adults with symptoms of depression from cognitive decline.
Combined Treatment With Naltrexone, Ketamine Effective for Depressive Symptoms
A combination of an opiate receptor antagonist with ketamine may reduce addiction risk in patients with depression.
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