Is There Genetic Overlap Between BMI and Major Psychiatric Disorders?
The findings suggest that factors such as antipsychotic treatment, diet, or lifestyle may contribute to weight gain in patients with long-term disease.
Depressive Disorder
Cortical Connectivity Patterns May Distinguish Antidepressant vs Placebo Response in Major Depressive Disorder
The trial enrolled patients with major depressive disorder from 4 clinical sites in the United States who were not receiving medication. Enrollees were randomly assigned to receive either sertraline hydrochloride or placebo for 8 weeks.
Largest Ever Genome-Wide Association Study Finds Genetic Risk Factors for Anxiety
In an analysis of polygenic risk scores, the researchers identified significant overlap between anxiety and major depressive disorder, as well as PTSD.
Resting State Connectivity Patterns May Predict Depression, ADHD in Children
The study provides strong evidence for the utility of resting-state fMRI measures in predicting the development of attentional or mood disorders in children.
Diet Quality Could Be a Key Treatment Target for Patients With Depression
Depression severity was correlated with dietary quality in patients who reported appetite loss.
Depression May Worsen Quality of Life in Rheumatoid Arthritis
Patients with coexisting rheumatoid arthritis (RA) and depression tend to have higher disease activity and lower quality of life than patients without depression.
Mental Distress, Depression Prevalent in Adults With Arthritis
The prevalence of mental distress is 16.8% and the prevalence of depression is 32.1% among adults with arthritis.
Label Error Prompts Recall of Antidepressant
Patients exposed to a higher dose than expected may be at increased risk of sedation, agitation, increased reflexes, tremor, sweating, dilated pupils, gastrointestinal distress, nausea, constipation and more.
Is There a Role for CBT as Maintenance Therapy to Prevent Depression Relapse?
Evidence suggests that antidepressant medication and CBT are similarly effective in acute treatment of MDD and combination therapy appears to be more effective in acute depressive episodes than either therapeutic approach alone.
Promising Findings for Dextromethorphan/Bupropion Treatment for Depression
Results showed that treatment with AXS-05 was associated with a statistically significant mean reduction from baseline in MADRS total score, compared with placebo at Week 6.
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