Nature or Nurture: Cross-Generational Transmission of Major Psychiatric Disorders
The findings identify genetics as the primary driver of parent-to-child bipolar disorder transmission, although childrearing elements may also contribute to risk.
Bipolar Disorders
Results of HOPE-BD Study Emphasize Importance of Early Intervention in Bipolar Disorder
The study emphasized the need to treat depression and other comorbidities, including anxiety and substance use disorders.
Schizophrenia and Bipolar Disorder May Share Sleep-Circadian Rhythm Phenotypes
Patients with bipolar disorder experienced significant reductions in sleep efficiency, which was not the case in patients with schizophrenia, although effect sizes for bipolar disorder were smaller overall.
Mental Health History May Be Associated With Increased Chronic Opioid Therapy Risk in RA
Researchers examined the association between mental health conditions and the risk for chronic opioid therapy in patients with rheumatoid arthritis.
No Evidence of Links Between Olfactory Dysfunction and Bipolar Disorder
Olfactory dysfunction is a marker for a number of neuropsychiatric disorders, including Parkinson disease, Alzheimer disease, and schizophrenia.
Patient Experiences With Antipsychotics Largely Negative, Survey Shows
Roughly two-thirds of patients categorized their experience with antipsychotics as more negative than positive and 34.9% endorsed an “extremely negative” experience.
Reproducible Epigentic Signature for Schizophrenia May Explain Gene-Environment Interactions
Working memory is impaired in schizophrenia, and epigenetic mechanisms such as DNA methylation may contribute to illness risk.
Opioid Overprescribing Observed Among Patients With Depression, Bipolar Disorder
Given the increased risk for opioid-related problems among patients with psychiatric diagnoses, the investigators advised a more cautious approach to prescribing that integrates expertise from mental health clinicians.
Psychiatric Disorders Share Common Neural Circuit, Emotion Processing Dysfunction
The results of the study point to the validity of the Research Domain Criteria initiative and suggest that neuroimaging findings may not be specific to certain psychiatric disorders.
Comorbid PTSD Raises Risk for Suicidal Ideation in Patients with Bipolar Disorder
Compared with patients without PTSD, patients with both bipolar disorder and PTSD were more likely to be women, on disability, have a lower education level, and have a lower annual household income.
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