Comorbid Bipolar I Disorder and Conduct Disorder May Represent a Distinct Familial Subtype
Comorbid bipolar I disorder and conduct disorder may represent a distinct familial subtype, providing valuable information for future clinicians.
Bipolar Disorders
Aripiprazole Augmentation Effective in Treatment of Comorbid Bipolar Disorder, OCD
Per 6 published studies, using aripiprazole to augment mood stabilizers was effective in reducing the symptoms of co-occurring bipolar disorder and obsessive-compulsive disorder.
CACNG2 Gene Nominally Associated With Lithium Response in Bipolar Disorder
Recent study results confirm previous findings that the CACNG2 gene is associated with both bipolar disorder and lithium responsiveness.
No Benefit Seen With Pioglitazone in Patients With Bipolar Depression
Study findings do not support the antidepressant efficacy of pioglitazone in the treatment of bipolar depression.
Aripiprazole Not Associated With Increased Hospitalizations, Suicidality in Patients Previously Treated With Antipsychotics
Introducing aripiprazole after previous antipsychotic exposure did not appear to increase serious psychiatric risk.
Depression Associated With Polygenic Risk for Major Depression, Bipolar Disorder, and Schizophrenia
Polygenic risk for major depression, bipolar, and schizophrenia is linked to depression in the general population.
Phone Contact Improved Medication Adherence in Severely Mentally Ill Patients
Telemedicine can deliver support to patients who are otherwise at high risk for progressive nonadherence to their psychotropic medication regimens.
Results From Bipolar I Disorder Trials Evaluating Brexpiprazole Announced
Data from two Phase 3 studies evaluating brexpiprazole for the treatment of patients with manic episodes associated with bipolar I disorder did not meet the primary endpoint of statistical separation from placebo as measured by the Young Mania Rating Scale at week 3.
Targeting Energy, Activity in Bipolar Disorder May Improve Quality of Life
Interventions targeting motor activity and energy may be more efficacious than current approaches targeting depressed mood in adults with bipolar disorder.
Lithium Preferred Method of Maintenance Monotherapy in Older Adults With Bipolar Disorder
Lithium continues to be the preferred method of maintenance monotherapy in older adults with bipolar disorder according to a Delphi survey.
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