Clinical Utility of Delay Discounting in Psychiatric Disorders
Delay discounting may be considered a transdiagnostic process across many psychiatric disorders, such as bipolar disorder and borderline personality disorder.
Bipolar Disorders
Parental Bipolar Disorder May Affect Presentation of Pediatric Bipolar Disorder
Children with pediatric bipolar disorder who had a parent with bipolar disorder showed a greater prevalence of comorbid ADHD compared with children with the same diagnosis but healthy parents.
Sex, Higher Illness Severity Associated With Bipolar Disorder II
Being female, having a family history of psychiatric conditions, and having higher illness severity are associated with bipolar disorder II.
Cognitive, Functional Remediation Show Promise in Bipolar Disorder
While investigators found support for the use of cognitive and functional remediation in patients with bipolar disorder, they stressed the need for additional randomized controlled trials.
Lithium Effective in Treating Youth With Bipolar Disorder
Consistent with research on adults with bipolar disorder, lithium is associated with decreased suicidality, better psychosocial functioning, and fewer depressive symptoms in children and adolescents.
Cariprazine Shows Efficacy for Bipolar Mania With Mixed Features
Cariprazine significantly reduced mixed features in patients with bipolar I disorder.
Targeting Psychosis, Depression, Cognition May Improve Functional Outcomes in Bipolar Disorder
Variables that significantly contributed to functional outcomes in bipolar disorder included a history of psychotic symptoms followed by depression and executive functioning and verbal memory.
Performance-Based Measures of Functional Capacity Correlated With Objective Cognition in Bipolar Disorder
Objectively measured cognition in patients with bipolar disorder was directly associated with performance-based functional capacity, but not with interview-based or self-reported functional capacity.
High Incidence of Psychopharmacologic Treatment Failure in Bipolar Disorder
Mood stabilizers and second-generation antipsychotics are associated with a high incidence of failure in bipolar disorder during the first year of treatment.
Adult Bipolar Disorder With or Without Childhood ADHD Difficult to Distinguish Using Cognitive Tests
Worse outcomes are associated with comorbid attention-deficit/hyperactivity disorder and bipolar disorder, but cognitive testing has limited differential value in identifying this group.
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