To date, there has not been proven evidence for serotonin-norepinephrine reuptake inhibitors over selective serotonin reuptake inhibitors in postmenopausal patients with major depressive disorder. Consequently, study researchers aimed to compare the efficacy and safety of venlafaxine vs fluoxetine in the treatment of postmenopausal MDD.
While known to increase patient compliance, medication organizers, such as blister packs and pill boxes, have also been associated with unintentional pediatric medication exposures.
While mental health disorders are prevalent among pregnant women, limited research, with limited strength of evidence has examined the effectiveness, benefits, and harms of pharmacotherapy for perinatal mental health disorders. Consequently, the researchers systematically reviewed evidence of pharmacotherapy for perinatal mental health disorders.
To better understand the conformational effects of psychedelic compounds, researchers developed psychLight, a genetically encoded biosensor that generates fluorescence in 5-HT2AR.
The designation is based on results from a phase 2 trial that evaluated the efficacy and safety of 4 different doses of BI 425809 orally once daily in adults with CIAS for 12 weeks.
Women who stopped antidepressant treatment during pregnancy and resumed in the following weeks had a rebound effect of increased prescription of benzodiazepines and anxiolytics.
Post-hoc analyses of pooled data from the randomized, double-blind ASPIRE 1 and ASPIRE II studies were conducted to assess the effect of esketamine in adult patients with major depressive disorder and active suicidal ideation.
Social engagement, posttraumatic growth, optimism, and resilience are psychological factors that play an essential role in positive psychiatry.
No evidence was found to support the concerns of international drug safety authorities regarding an increased risk for suicidality in young people treated with antidepressants.
Results showed that discontinuation of any SNRI was associated with withdrawal symptoms, with the highest prevalence linked to venlafaxine and desvenlafaxine.
