Illicit Stimulant-Involved Mortality Rates Rapidly Rising in the United States
Stimulant mortality has been on the rise since 2010 with a doubling of the mortality rate every 4 years.
Addiction
THC Linked to Neuropsychiatric Side Effects in Older Adults
To clarify the potential side effects of THC exposure in older adults, investigators conducted a systematic review of RCTs reporting the safety and efficacy of various cannabinoid-based medicines in adults older than 50 years.
Controversy: Protecting People Who Use Drugs During COVID-19
Anna Lembke, MD, discusses how patients who use drugs are affected by the convergence of 2 public health emergencies – increasing overdose rates, and the COVID-19 pandemic – and addresses controversial solutions proposed by other investigators.
Many Opioid Prescribers View Patient Provider Agreements as Unhelpful in Minimizing Opioid Misuse
Most PPAs in prescribers’ practices focused on rules and consequences of noncompliance instead of on a shared treatment plan.
Stimulant Overdose Among Youth Is on the Rise
While previous studies have looked at opioid use among youth, information is lacking on heroin and stimulant overdose rates. The researchers investigated trends in suspected nonfatal drug overdoses (all drugs, opioids, heroin, and stimulants) reported to emergency departments between 2016 and 2019
Targeting GLP-1R Protein May Curb Cocaine-Seeking Behavior
This study examines neural circuits and cell types that mediate the suppressive effect of GLP-1R agonists on cocaine-seeking behaviors.
Intensive Counseling Improves Smoking Cessation Rates in Patients With Cancer
Patients with cancer who receive intense smoking cessation treatment are compared with patients who receive standard treatment to analyze the intervention’s impact on the likelihood of quitting smoking.
COVID-19 Stress Caused Some to Start Using Drugs, Alcohol
With COVID-19 having truly disastrous effects, the study authors sought to uncover the toll of substance abuse during the pandemic.
Bupropion-Naltrexone Bests Placebo in Methamphetamine Use Disorder
For adults with methamphetamine use disorder, response is higher with receipt of extended-release injectable naltrexone plus oral extended-release bupropion versus placebo.
Substance Use Disorder Associated With an Increased Risk of Adverse COVID-19 Outcomes
Researchers analyzed how substance use disorder affected the risk of hospitalization, complications and mortality among adult patients who were diagnosed with having a COVID-19 infection.
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