The updated recommendations include both nonpharmacologic and pharmacologic interventions for adults in the acute phase of MDD.
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Auvelity is supplied as dextromethorphan HBr 45 mg/bupropion HCl 105 mg extended-release tablets in 30-count bottles.
Investigators studied the safety and efficacy of zuranolone, a neuroactive steroid γ-aminobutyric acid receptor-positive allosteric modulator, for women with postpartum depression.
To date, there has not been proven evidence for serotonin-norepinephrine reuptake inhibitors over selective serotonin reuptake inhibitors in postmenopausal patients with major depressive disorder. Consequently, study researchers aimed to compare the efficacy and safety of venlafaxine vs fluoxetine in the treatment of postmenopausal MDD.
With most studies only focusing on interhemispheric connectivity in major depressive disorder (MDD), the researchers looked at brain functional connectivity asymmetry in MDD.
Findings further increase concerns about the continuing lack of mental health treatment use, particularly given the recent policy focus on perinatal depression.
Researchers examined whether more severe appetitive symptoms predicted a positive response to light therapy.
Among men, those with active major depression were less likely to have a partner achieve conception.
Motor impulsivity is a strong predictor of suicidal actions in patients with bipolar disorder or major depressive disorder.
Electroconvulsive therapy may be more beneficial for the treatment of acute-phase depression than fluoxetine.
Patients with depression can benefit from online cognitive behavior therapy programs.
Major depressive disorder could find a potential new treatment in SAGE-217, which received FDA fast track designation.
Expert discusses identifying and managing nutrient deficiencies or eating habits that can contribute to mental health conditions including depression and anxiety.
Given the ethnic and racial disparities in the US, researchers examined whether SDoH contributed to racial and ethnic disparities in cognition, health, and depression.
Researchers examined prospective associations between insomnia symptoms and prescription opioid and benzodiazepine misuse.
Researchers compared the white matter networks of patients with remitted major depressive disorder and remitted bipolar disorder to find disease-specific alterations.
In a prospective cohort study, researchers assessed whether adverse childhood experiences may increase the risk for multiple sclerosis in women.
Data for this study were sourced from 4 active treatment arms of 4 randomized, controlled trials conducted by the National Institutes of Health in the United States between 2006 and 2018.
Investigators conducted a scoping review of randomized controlled trials that evaluated the impact of cognitive behavioral therapy on symptoms of depression and anxiety among patients with type 2 diabetes.
A deep dive into clinical efficacy and safety of using psychedelic-assisted psychotherapy for depression, anxiety, PTSD, substance use disorder, and other mental health disorders.
Investigators from Oklahoma State University Center for Health Sciences evaluated randomized controlled trials of MDD published between 2016 and 2020 for the quality of their PRO reporting.
In a sample of young people, the genetic and environmental architecture of hypomanic symptoms were compared with the levels of severity and if they had any association with bipolar disorder.
The researchers’ goal was to explore the efficacy of cognitive-behavioral therapy for psychosis in patients with a high clinical risk for psychosis.
Diabetic neuropathic pain is associated with depression, anxiety, sleep disorders, and lower quality of life in patients with type 2 diabetes.
Post-ICU syndrome includes psychological effects — depression, anxiety, and PTSD — as well as worsened physical functioning.
Youth who completed a computer-based intervention reported longer time to first postvisit cannabis use and a lower rate of riding with an impaired driver.
Treatment with benzodiazepines for less than 3 months may not decrease the cognitive function of patients with major depressive disorder who are also prescribed antidepressants.
Parkinsonism is a lesser known debilitating adverse effect associated with valproate, especially in older patients.
Researchers found study data that in patients with primary aldosteronism, men have higher blood pressure and body mass index levels, but women with primary aldosteronism have significant associations between blood pressure and anxiety and depressive symptoms.
MAOIs appear to be effective for patients with early stage treatment-resistant depression compared to tricyclic antidepressants, but efficacy seems to diminish as prior antidepressant exposure increases.
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