Researchers assessed the effectiveness of COVID-19 booster vaccination against severe, critical, and fatal COVID-19 infection.
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Researchers investigate the association between transgender women and prostate cancer.
Implementation of minimum unit pricing for alcohol has led to significant reductions in deaths and hospitalizations wholly attributable to alcohol consumption.
There is an increased risk of T2D in young adults who use SSRIs or SNRIs.
Menopausal women who took an SSRI had a 76% higher risk of fracture after one year of use compared to women not taking an antidepressant.
The issue of whether and how prenatal SSRI exposure affects offspring has remained murky.
Concomitant SSRI/SNRI use was associated with an increased diabetes risk in AAP-treated young people.
Pimavanserin, either alone or in conjunction with a selective serotonin reuptake inhibitor or serotonin–norepinephrine reuptake inhibitor, may improve comorbid depression symptoms in patients with Parkinson disease.
Elevated cytokine levels could help to identify children who are unlikely to respond to treatment with fluoxetine.
Concomitant use of oral anticoagulants among people taking SSRIs contributed to a significantly higher risk for ICH.
Several promising novel treatment options exist for those with OCD.
In this randomized clinical trial of participants with social anxiety disorder, investigators examined how manipulation of verbally-induced expectancies, vital for placebo response, affect brain monoamine transporters and symptom improvement during SSRI treatment.
When combined with other serotonergic agents, selective serotonin reuptake inhibitors can lead to a potentially fatal condition called serotonin syndrome, the incidence of which is likely underestimated.
In an 8-week open-label extension, escitalopram plus ziprasidone was found to be safe in certain patients, requiring regular cardiovascular and metabolic monitoring.
While antipsychotics are useful in some types of anxiety disorders, cognitive-behavioral therapy may be preferable in others.
Investigators searched publication databases through January 2021 for placebo-controlled studies of treatment for MDD among pediatric patients.
COVID-19 mRNA vaccine boosters increase antibody duration, but do not increase antibody levels.
While mental health disorders are prevalent among pregnant women, limited research, with limited strength of evidence has examined the effectiveness, benefits, and harms of pharmacotherapy for perinatal mental health disorders. Consequently, the researchers systematically reviewed evidence of pharmacotherapy for perinatal mental health disorders.
Paroxetine use improved cognitive impairment and reduced inflammation in HIV patients.
Personalized medicine “promises to move beyond data regarding the average effectiveness of treatments to identify the best treatment for any individual.” However, personalized medicine for depression necessitates “identifying characteristics of individuals that reliably predict differences in benefits and/or adverse effects of alternative depression treatments, including both biological and psychosocial treatments.”
Although a recent study indicates that treatment with SSRI antidepressants may help, CBT remains the primary form of therapy.
This study summarizes current literature for the effect of borderline personality disorder on the treatment response and management of patients affected by major depressive disorder.
Findings showed that the booster dose elicited robust antibody responses comparable to, or exceeding levels associated with the efficacy data in the primary series of the vaccine.
The submission is supported by data from the phase 3 PREVENT-19 trial and the phase 2 COV-BOOST trial.
Convincing evidence was observed for an association between SSRI use and increased risk for suicide attempt or completion in children and adolescents.
Receipt of a third COVID-19 mRNA vaccine dose is associated with increased vaccine effectiveness against COVID-19 hospitalization.
The Novavax COVID-19 Vaccine, Adjuvanted is administered intramuscularly as a 2-dose primary series (0.5 mL each), separated by 3 weeks.
The relationship between agoraphobia and panic has gone through some changes and reconceptualization, as evidenced by the diagnostic categories laid out in the Diagnostic and Statistical Manual of Mental Disorders.
The study authors investigated the fatigue that can take place in video calls and/or by the additional cognitive load these calls require.
Investigators found data that showed that patients with major depressive disorder who had been treated with more than 2 antidepressants, including an SNRI, showed a low likelihood of response to venlafaxine at any dosage.
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