Schizophrenia

Childhood Insulin Resistance Associated With Later Psychosis

Childhood Insulin Resistance Associated With Later Psychosis

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The authors advised clinicians to carefully consider which antipsychotics they prescribe their patients with metabolic dysfunction, as some are known to be diabetogenic.

Haloperidol Associated With Slight Increased Risk for Death in Acute Myocardial Infarction

Haloperidol Associated With Slight Increased Risk for Death in Acute Myocardial Infarction

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These data may be useful to clinicians in considering the risks and benefits of prescribing haloperidol for patients with cardiac morbidity.

Violence in Schizophrenia Associated With Several Risk Factors at Diagnosis

Violence in Schizophrenia Associated With Several Risk Factors at Diagnosis

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In patients with a history of pre-diagnostic violence, a history of non-violent offending in the 18-month period pre-diagnosis was the strongest predictor of future violence.

Clinical Outcomes Assessed for Major Depressive Disorder With Psychotic Features

Clinical Outcomes Assessed for Major Depressive Disorder With Psychotic Features

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Major depressive disorder with psychotic features had comparative long-term outcomes with schizophrenia, schizoaffective disorder, and bipolar disorder.

Exploring Brain Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia

Exploring Brain Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia

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The authors pointed to a possible difference in the specific symptoms alleviated by different types of stimulation.

Recovery From First Episode Psychosis More Likely in Those With Mania, Brief Psychosis Diagnoses

Recovery From First Episode Psychosis More Likely in Those With Mania, Brief Psychosis Diagnoses

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The early sustained recovery group was more likely to have a diagnosis other than schizophrenia, particularly mania or brief psychosis.

Old Challenges and New Directions in Managing Tardive Dyskinesia

Old Challenges and New Directions in Managing Tardive Dyskinesia

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"Since the current generation of psychiatrists has been raised on second-generation antipsychotics and has relatively little experience with first-generation antipsychotics, keeping tardive dyskinesia in mind is not, on the whole, part of their experience or training," said Christoph U. Correll, MD.

Negative Symptoms Increase Cardiovascular Risk in Schizophrenia

Negative Symptoms Increase Cardiovascular Risk in Schizophrenia

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Although various clinical and psychosocial factors were associated with unhealthy lifestyle factors and higher risk for CVD, the strongest associations were with negative symptoms.

Cognitive Impairment May Predict Persistent Psychosis in Ketamine Users

Cognitive Impairment May Predict Persistent Psychosis in Ketamine Users

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Ketamine-dependent patients who exhibited psychosis demonstrated levels of spatial problem solving and verbal memory impairment similar to those of patients with schizophrenia.

Improving Performance of Everyday Activities Is Critical in Schizophrenia

Improving Performance of Everyday Activities Is Critical in Schizophrenia

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Treatment beyond antipsychotic drugs is needed for people with schizophrenia, as positive symptoms are a peripheral node in the network.

Heavy Cigarette Smoking in Adolescence May Increase Risk for Psychosis

Heavy Cigarette Smoking in Adolescence May Increase Risk for Psychosis

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Despite the recognition that early daily tobacco use likely increases the risk for later psychosis, investigation of the effect of covariates such as substance use, existing psychotic features, or parental/family factors was lacking in the literature.

CBT Plus Cognitive Remediation May Improve Vocational Outcomes in Schizophrenia

CBT Plus Cognitive Remediation May Improve Vocational Outcomes in Schizophrenia

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These results suggest that CBT alone may be insufficient in enhancing work outcomes in patients with schizophrenia, despite its efficacy in treating other symptoms.

Adjunctive Raloxifene May Improve Psychotic Symptoms in Postmenopausal Women With Schizophrenia

Adjunctive Raloxifene May Improve Psychotic Symptoms in Postmenopausal Women With Schizophrenia

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The meta-analysis showed raloxifene to be effective for positive symptoms, negative symptoms, and general psychopathology, with greatly homogeneous results.

Noninvasive Brain Stimulation May Improve Negative Schizophrenia Symptoms

Noninvasive Brain Stimulation May Improve Negative Schizophrenia Symptoms

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The findings of this meta-analysis suggested that both repetitive transcranial magnetic stimulation and transcranial direct current stimulation were significantly more effective at improving negative symptoms than sham stimulation.

Infection in First Year Has Greatest Effect on IQ, Nonaffective Psychosis

Infection in First Year Has Greatest Effect on IQ, Nonaffective Psychosis

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Investigators determined infections in the first year of life to be the "sensitive period" for risk of adult nonaffective psychosis.

Emergency Mental Health Services During Hurricane Harvey: Challenges and Lessons

Emergency Mental Health Services During Hurricane Harvey: Challenges and Lessons

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Bipolar disorder (31.9%), depression (19.8%), schizophrenia (14.2%), and anxiety disorders (9.1%) were the most common mental health issues reported. Approximately 13% of evacuees with a mental health concern reported a history of post-traumatic stress disorder.

Children Bullied by Sibling at Increased Risk of Developing a Psychotic Disorder

Children Bullied by Sibling at Increased Risk of Developing a Psychotic Disorder

Children who are involved in sibling bullying are at a higher risk of developing a psychotic disorder.

Plasma Autoantibodies Possible Biomarker for Schizophrenia

Plasma Autoantibodies Possible Biomarker for Schizophrenia

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Investigators selected 15 genes associated with schizophrenia due to high expression in both brain tissue and B-lymphocyte cells.

Amisulpride May Be Most Effective Antipsychotic for Negative Symptoms in Schizophrenia

Amisulpride May Be Most Effective Antipsychotic for Negative Symptoms in Schizophrenia

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There has been a question of whether antipsychotic medications are truly acting upon "primary" negative symptoms, or whether they are instead improving "secondary" negative symptoms via improvement in positive or depressive symptoms.

Cost-Effectiveness of Paliperidone Palmitate in Schizophrenia With Cardiometabolic Comorbidities

Cost-Effectiveness of Paliperidone Palmitate in Schizophrenia With Cardiometabolic Comorbidities

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Although all-cause pharmacy costs were higher in the paliperidone palmitate group, adjusted all-cause medical costs were lower.

Virtual Reality Can Reduce Anxiety, Improve Social Interactions in Psychosis

Virtual Reality Can Reduce Anxiety, Improve Social Interactions in Psychosis

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Use of virtual reality environments in which participants interact with computer-controlled situations or avatars enables a more fine-tuned approach to exposure in the context of cognitive behavioral therapy.

Addition of SSRIs to Antipsychotics Has Only Minor Impact on Metabolic Risk Factors

Addition of SSRIs to Antipsychotics Has Only Minor Impact on Metabolic Risk Factors

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A combination of an SSRI and antipsychotics in a clinical setting most likely does not lead to a further deterioration of metabolic variables to a clinically significant degree.

Psychosis Associated With Increased Complications Following Total Joint Arthroplasty

Psychosis Associated With Increased Complications Following Total Joint Arthroplasty

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Investigators seek the association between psychosis and complication risk after total joint arthroplasty.

Suppression of Auditory Stimuli Associated With Pathologic Symptoms of Schizophrenia

Suppression of Auditory Stimuli Associated With Pathologic Symptoms of Schizophrenia

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P50 processing may inform researchers in the future development of interventions targeting cognitive impairment in schizophrenia.

Substance-Induced Psychosis Associated With Development of Schizophrenia, Bipolar Disorder

Substance-Induced Psychosis Associated With Development of Schizophrenia, Bipolar Disorder

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All patients with a substance-induced psychosis should be offered follow-up.

Cognitive Insight Impairment May Precede Neurocognitive Decline in Schizophrenia

Cognitive Insight Impairment May Precede Neurocognitive Decline in Schizophrenia

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This research suggests that interventions to improve cognitive insight may bolster neurocognition in schizophrenia.

Examining Metabolic Concerns Associated With Antipsychotics in Schizophrenia

Examining Metabolic Concerns Associated With Antipsychotics in Schizophrenia

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Twelve antipsychotics, including olanzapine, ziprasidone, and lurasidone, were examined in a meta-analysis.

Antidepressant Effectiveness for Depression in Schizophrenia

Antidepressant Effectiveness for Depression in Schizophrenia

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Antidepressants may effectively treat depression in patients with comorbid schizophrenia.

Monetary Incentives Improve Cessation in Mentally Ill Smokers

Monetary Incentives Improve Cessation in Mentally Ill Smokers

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Abstinence-contingent incentives improved smoking cessation outcomes among economically disadvantaged smokers with mental illness.

Understanding the Links Between Schizophrenia and Sleep Disorders

Understanding the Links Between Schizophrenia and Sleep Disorders

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A growing body of research consistently shows that patients with schizophrenia often suffer from sleep disturbances.

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