Schizophrenia

Plasma Autoantibodies Possible Biomarker for Schizophrenia

Plasma Autoantibodies Possible Biomarker for Schizophrenia

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Investigators selected 15 genes associated with schizophrenia due to high expression in both brain tissue and B-lymphocyte cells.

Amisulpride May Be Most Effective Antipsychotic for Negative Symptoms in Schizophrenia

Amisulpride May Be Most Effective Antipsychotic for Negative Symptoms in Schizophrenia

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There has been a question of whether antipsychotic medications are truly acting upon "primary" negative symptoms, or whether they are instead improving "secondary" negative symptoms via improvement in positive or depressive symptoms.

Cost-Effectiveness of Paliperidone Palmitate in Schizophrenia With Cardiometabolic Comorbidities

Cost-Effectiveness of Paliperidone Palmitate in Schizophrenia With Cardiometabolic Comorbidities

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Although all-cause pharmacy costs were higher in the paliperidone palmitate group, adjusted all-cause medical costs were lower.

Virtual Reality Can Reduce Anxiety, Improve Social Interactions in Psychosis

Virtual Reality Can Reduce Anxiety, Improve Social Interactions in Psychosis

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Use of virtual reality environments in which participants interact with computer-controlled situations or avatars enables a more fine-tuned approach to exposure in the context of cognitive behavioral therapy.

Addition of SSRIs to Antipsychotics Has Only Minor Impact on Metabolic Risk Factors

Addition of SSRIs to Antipsychotics Has Only Minor Impact on Metabolic Risk Factors

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A combination of an SSRI and antipsychotics in a clinical setting most likely does not lead to a further deterioration of metabolic variables to a clinically significant degree.

Psychosis Associated With Increased Complications Following Total Joint Arthroplasty

Psychosis Associated With Increased Complications Following Total Joint Arthroplasty

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Investigators seek the association between psychosis and complication risk after total joint arthroplasty.

Suppression of Auditory Stimuli Associated With Pathologic Symptoms of Schizophrenia

Suppression of Auditory Stimuli Associated With Pathologic Symptoms of Schizophrenia

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P50 processing may inform researchers in the future development of interventions targeting cognitive impairment in schizophrenia.

Substance-Induced Psychosis Associated With Development of Schizophrenia, Bipolar Disorder

Substance-Induced Psychosis Associated With Development of Schizophrenia, Bipolar Disorder

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All patients with a substance-induced psychosis should be offered follow-up.

Cognitive Insight Impairment May Precede Neurocognitive Decline in Schizophrenia

Cognitive Insight Impairment May Precede Neurocognitive Decline in Schizophrenia

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This research suggests that interventions to improve cognitive insight may bolster neurocognition in schizophrenia.

Examining Metabolic Concerns Associated With Antipsychotics in Schizophrenia

Examining Metabolic Concerns Associated With Antipsychotics in Schizophrenia

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Twelve antipsychotics, including olanzapine, ziprasidone, and lurasidone, were examined in a meta-analysis.

Antidepressant Effectiveness for Depression in Schizophrenia

Antidepressant Effectiveness for Depression in Schizophrenia

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Antidepressants may effectively treat depression in patients with comorbid schizophrenia.

Monetary Incentives Improve Cessation in Mentally Ill Smokers

Monetary Incentives Improve Cessation in Mentally Ill Smokers

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Abstinence-contingent incentives improved smoking cessation outcomes among economically disadvantaged smokers with mental illness.

Understanding the Links Between Schizophrenia and Sleep Disorders

Understanding the Links Between Schizophrenia and Sleep Disorders

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A growing body of research consistently shows that patients with schizophrenia often suffer from sleep disturbances.

AVATAR Therapy Reduces Auditory Verbal Hallucinations in Schizophrenia

AVATAR Therapy Reduces Auditory Verbal Hallucinations in Schizophrenia

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AVATAR therapy significantly reduced the severity of hallucinations compared with supportive counseling.

Association of Schizophrenia-Related Polygenic-Risk Score Across Bipolar Disorder Subtypes

Association of Schizophrenia-Related Polygenic-Risk Score Across Bipolar Disorder Subtypes

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A schizophrenia-related polygenic-risk score association gradient was identified across bipolar disorder phenotypes.

Psychotic Symptom Severity in BPAD Inversely Linked to Lithium Response

Psychotic Symptom Severity in BPAD Inversely Linked to Lithium Response

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The severity of psychotic symptoms in patients with bipolar affective disorder correlated inversely with the response to lithium therapy.

Predictors of Aggression in Patients With Bipolar Disorder, Schizophrenia

Predictors of Aggression in Patients With Bipolar Disorder, Schizophrenia

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Patients with schizophrenia-spectrum disorders had higher odds of being aggressive than people with bipolar disorder with a recent manic episode.

Neuropsychiatric Symptoms Occur More Frequently in Relatives of Patients With ALS

Neuropsychiatric Symptoms Occur More Frequently in Relatives of Patients With ALS

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Family members of ALS patients have higher rates of neuropsychiatric conditions.

Readmission Risk for Schizophrenia Associated With Younger Age

Readmission Risk for Schizophrenia Associated With Younger Age

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For patients with schizophrenia or schizoaffective disorder, younger age was significantly associated with an increased rate of readmission.

Risk of Schizophrenia May Be Impacted by Inflammatory Biomarkers

Risk of Schizophrenia May Be Impacted by Inflammatory Biomarkers

The risk of developing schizophrenia may be impacted by specific inflammatory biomarkers.

Transcranial Stimulation Reduces Auditory Hallucinations in Schizophrenia

Transcranial Stimulation Reduces Auditory Hallucinations in Schizophrenia

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Transcranial direct current stimulation might aid patients with schizophrenia who experience auditory hallucinations.

Lurasidone Reduces Agitation in Acute Exacerbation of Schizophrenia

Lurasidone Reduces Agitation in Acute Exacerbation of Schizophrenia

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Lurasidone reduced agitation in patients with acute exacerbation of schizophrenia.

People With Schizophrenia More Likely to Die at a Younger Age

People With Schizophrenia More Likely to Die at a Younger Age

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People with schizophrenia have a mortality rate 3 times higher than the general population, which may be linked to higher rates of smoking, alcohol consumption, poor diet, and lack of exercise in people with schizophrenia.

Quality of Diabetes Care Low Among Patients With Schizophrenia

Quality of Diabetes Care Low Among Patients With Schizophrenia

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The quality of diabetes care was examined in patients with and without schizophrenia in a Danish nationwide cohort.

Long-Acting Injectable Antipsychotics Delay Schizophrenia Relapse

Long-Acting Injectable Antipsychotics Delay Schizophrenia Relapse

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In patients with schizophrenia, long-acting injectable formulations of paliperidone palmitate delay relapse significantly after withdrawal.

Elevated Dopamine Synthesis Capacity Observed in Both Bipolar and Schizophrenia

Elevated Dopamine Synthesis Capacity Observed in Both Bipolar and Schizophrenia

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Dopamine dysfunction underlies the pathoetiology of psychosis in both bipolar disorder and schizophrenia.

Predictors of Development of Early Onset Psychosis in Parkinson Disease

Predictors of Development of Early Onset Psychosis in Parkinson Disease

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Researchers conducted a prospective case-control study to examine predictors of early and late-onset psychosis in Parkinson disease.

Persistent Negative Symptoms in First-Episode Psychosis Associated With Early Onset of Disease

Persistent Negative Symptoms in First-Episode Psychosis Associated With Early Onset of Disease

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These findings suggest that there are critical periods of development associated with a higher risk of persistent negative symptoms.

New Performance-Based Tool Evaluates Cognitive Impact of Schizophrenia

New Performance-Based Tool Evaluates Cognitive Impact of Schizophrenia

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In this study, 672 patients with schizophrenia were evaluated with the EPICOG-SCH brief cognitive battery.

Signs of Schizophrenia That Should Not Be Ignored

Signs of Schizophrenia That Should Not Be Ignored

Seven signs and symptoms might alert someone to the possible presentation of schizophrenia.

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