Interventions focused on emotion recognition may be effective in addressing sociocognitive deficits in patients with schizophrenia.
A team of UK-based investigators assessed functional and symptomatic outcomes in individuals with a first episode of psychotic disorder vs those associated with schizophrenia.
In an attempt to identify the risk associated with the comorbidity of type 2 diabetes and schizophrenia, a team of investigators from Taiwan assessed the impact of public health promotion efforts targeted at this population.
This research supports the monitoring of metabolic syndrome in patients with schizophrenia.
Lumateperone, a first-in-class molecule, works via potent interactions at 5-HT2A receptors, serotonin transporters, and D1 receptors with indirect glutamatergic modulation.
These data suggest that residential mobility may have a profound effect on the mental well-being of children and adolescents.
Timely categorization of patients as treatment-resistant or responsive may allow faster implementation of better targeted interventions.
In conclusion, these preliminary findings suggest that quetiapine is not a teratogen and could be used safely during pregnancy, but further research is needed to completely understand the risks involved.
Future studies should investigate how supplementation with vitamin D may improve symptoms and outcomes.
The study exhibited an overall conversion rate of 35% to a psychotic disorder.
Remission can be achieved for most cases of schizophrenia and schizophreniform disorder with amisulpride and clozapine.
The authors argue that identifying and treating sleep disorders during early stages may have a positive impact on outcomes in psychiatric patients.
Despite the associated risk for death and cognitive decline, "off-label" prescribing of antipsychotics in patients with dementia has increased.
The dose-response relationship observed between CBT and schizophrenia outcome may be salient to clinicians in titrating treatment strategies.
There was a significantly higher level of prolactin found in the first episode psychosis group than in the clinical high risk group, suggesting a condition of hyperprolactinemia.
Researchers found a suicide attempt rate of 12.0% in first-episode, drug-naive inpatients.
The findings support second generation long-acting injectable antipsychotic drug use as early treatment option to increase treatment adherence and to decrease the risk of relapse, hospitalization, and deteriorating social functions.
WSE treatment may be useful in addressing symptom exacerbation in schizophrenia and schizoaffective disorder.
Investigators examined factors that may improve employment in patients with schizophrenia.
Perseris, an atypical antipsychotic, has an extended-release delivery system that releases sustained levels of risperidone over 1 month.
These results may be helpful for clinicians when considering the effects of antipsychotic intervention on patient high-density lipoprotein cholesterol levels.
Inhalant and other substance use during adolescence are increasingly associated with many adverse health and psychosocial outcomes.
These data have implications for the efficacy of the US military healthcare system as a whole in treating psychosis in service members.
FDA Approval of Medication With a Digital Monitoring System: Major Breakthrough or "Brave New World"?July 23, 2018
Abilify MyCite adds a digital sensor to the medication aripiprazole. The sensor, an ingestible event marker, is activated by contact with stomach acids and transmits a signal to a skin patch the patient wears, which then transmits to an app.
As psychosis and substance use disorder comorbidity can make oral medication adherence difficult, long-acting injectable agents may be an effective therapeutic alternative in patients in this demographic.
Each of the studied brain modalities could be classified as "gray matter abnormalities" or "white matter disruptions" and may be significant in the pathology of schizophrenia.
This study created a validated model for determining brain age and brain age gap, which then can be used to predict early-onset psychosis in younger clinically high-risk adolescents who exhibit prodromal symptoms.
The findings of this study contribute to the understanding of the neurodevelopmental cognitive vulnerability in middle childhood for the children of people with either schizophrenia or bipolar disorder.
These data suggest that aripiprazole can be safely used in premenopausal women to treat elevated prolactin levels and prolactin-related adverse effects.
Atypical antipsychotic use was associated with a higher risk for cardiovascular events among publicly insured youth in the US.
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Psychiatry Advisor Articles
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- Early Risk Factors for Bipolar Disorder Found in Offspring of BD Parents
- First-Episode Delusional Disorder vs Schizophrenia: Assessment of Outcomes
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- Probiotics, Depression, and the Role of Inflammation
- The Opioid System: The Foundation for Social Risk and Reward
- Correctional Psychiatry: Challenges and Rewards
- Those Left Behind: Working With Suicide-Bereaved Families
- Is Mandatory Reporting of Child Maltreatment in the Best Interests of the Child?
- The Impact of Deafness on Hallucinations and Delusions
- High Risk for Anxiety, Depression, and Stress Observed Among Single Mothers
- Self-Harm, Suicidality Among Adolescents Associated With Poor Outcomes, Recurrent Clinical Care
- Moderate Association Between Sociocognitive Functioning and Thought Disorder in Schizophrenia
- Psychotropic Medications May Improve Pregnancy Outcomes in Bipolar Disorder
- Schizophrenia Polygenetic Risk Score as a Predictor of Bipolar Disorder With Psychosis