- Psychiatry Advisor

Psych YIR SCHIZOPHRENIA

YEAR IN REVIEW: SCHIZOPHRENIA

Lower Parental Income Associated With Schizophrenia

Although prior research suggests that heritability accounts for 66% to 85% of schizophrenia risk, additional risk factors include stress and the “nature of caregiving,” or the home environment and caregiver conduct.

Novel Treatment for Schizophrenia Gets FDA’s Breakthrough Therapy Designation

The Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to SEP-363856 (Sunovion), an investigational treatment for schizophrenia. SEP-363856 is believed to work by activating trace amine-associated receptor 1 (TAAR1) in addition to 5-HT1A receptors; unlike other antipsychotics, this novel agent does not bind to D2 or 5-HT2A receptors. The Breakthrough Therapy designation was…