Schizophrenia & Psychoses
A substantial proportion of these individuals diagnosed with HIV, psychiatric disorders, and substance use disorders are out of care and urgently require intervention.
The superior benefit provided by early intervention services for schizophrenia could be cost-effective, and the researchers call for widespread implementation and funding of early intervention services in the United States and globally.
These data may be helpful in titrating care for those with schizotypal disorder and comorbid substance abuse disorders to mitigate the risk for conversion to schizophrenia.
These data may be useful to clinicians in considering the risks and benefits of prescribing haloperidol for patients with cardiac morbidity.
The authors pointed to a possible difference in the specific symptoms alleviated by different types of stimulation.
The early sustained recovery group was more likely to have a diagnosis other than schizophrenia, particularly mania or brief psychosis.
Although various clinical and psychosocial factors were associated with unhealthy lifestyle factors and higher risk for CVD, the strongest associations were with negative symptoms.
Treatment beyond antipsychotic drugs is needed for people with schizophrenia, as positive symptoms are a peripheral node in the network.
The meta-analysis showed raloxifene to be effective for positive symptoms, negative symptoms, and general psychopathology, with greatly homogeneous results.
Investigators selected 15 genes associated with schizophrenia due to high expression in both brain tissue and B-lymphocyte cells.
Use of virtual reality environments in which participants interact with computer-controlled situations or avatars enables a more fine-tuned approach to exposure in the context of cognitive behavioral therapy.
Investigators seek the association between psychosis and complication risk after total joint arthroplasty.
P50 processing may inform researchers in the future development of interventions targeting cognitive impairment in schizophrenia.
The FDA issued a refusal to file letter for a new drug application.
Researchers from the University of Texas Southwestern Medical Center have discovered the cellular receptor that causes weight gain from antipsychotic drugs.
Shared decision making encourages a clinical partnership that can result in optimal treatment outcomes.
Increases in autonomic function may predict the occurrence and severity of auditory hallucinations in patients with schizophrenia, suggesting a regulation of these experiences by the autonomic nervous system.
The FDA has approved a new treatment for adolescents between the ages of 13 and 17 years who are diagnosed with schizophrenia.
Researchers profiled which young people may do well after first-episode psychosis without medication.
These study results indicate that early intervention with low doses of metformin in patients with few metabolic abnormalities may be beneficial.
Inability to interpret facial expressions may exacerbate psychotic symptoms, either indirectly via social defeat or directly by creating confusing interpersonal experiences.
PUFA supplementation offers little additional aid to psychosis when good psychosocial care is already sought.
Data indicate that 693 genes are differentially expressed between individuals diagnosed with schizophrenia and typical, healthy controls.
Dr. Scott Zeller suggests it is time to move away from emergency intramuscular haloperidol.
Researchers studied social cognition and social problem solving in patients with schizophrenia by employing a validated test designed to assess emotion recognition abilities.
Study provides further evidence for the effects of white matter fiber abnormalities and neuroinflammation on positive symptoms in patients with schizophrenia.
New findings provide an insight about the association between white matter microstructure and the severity of schizophrenia clinical symptoms.
Interaction of Proline and COMT Genotype Influences Negative Symptoms in Schizophrenia & Bipolar DisorderSeptember 27, 2016
The authors explored whether valproate (VPA) treatment effects vary by catechol-O-methyltransferase (COMT) genotype.
Poor psychosocial functioning among individuals diagnosed with schizophrenia is associated with deficits in social cognition.
TSPO expression is frequently used as a biomarker for brain inflammation during PET imaging.
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Psychiatry Advisor Articles
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- Etiology of Schizophrenia: Strong Association With Certain Rare Copy Number Variants
- KCNQ Channel Potentiator Ezogabine Delivers Promising Results in Major Depressive Disorder
- Vulnerability to Psychosocial Disability in Psychosis
- FDA to Review Lumateperone for Treatment of Schizophrenia
- Cannabis Use, Cannabis Use Disorder Linked to Psychotic, Depressive Symptoms
- Abstinence From Regular Cannabis Use Improves Memory Among Adolescents, Young Adults
- Association Between Opioid and Benzodiazepine Misuse and Suicidal Ideation
- Group Cognitive Behavioral Therapy Is Effective Treatment for Adolescent Anxiety
- The Intersection of Eating and Alcohol Disorders: Detecting and Managing "Drunkorexia"