Schizophrenia & Psychoses

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

HIV Viral Suppression Rates in Psychiatric Inpatients With Comorbid Substance Use Disorders

By

A substantial proportion of these individuals diagnosed with HIV, psychiatric disorders, and substance use disorders are out of care and urgently require intervention.

Early Intervention Services Superior to Treatment as Usual for Early-Phase Psychosis

Early Intervention Services Superior to Treatment as Usual for Early-Phase Psychosis

By

The superior benefit provided by early intervention services for schizophrenia could be cost-effective, and the researchers call for widespread implementation and funding of early intervention services in the United States and globally.

Substance Use Disorders Associated With Conversion From Schizotypal Disorder to Schizophrenia

Substance Use Disorders Associated With Conversion From Schizotypal Disorder to Schizophrenia

By

These data may be helpful in titrating care for those with schizotypal disorder and comorbid substance abuse disorders to mitigate the risk for conversion to schizophrenia.

Haloperidol Associated With Slight Increased Risk for Death in Acute Myocardial Infarction

Haloperidol Associated With Slight Increased Risk for Death in Acute Myocardial Infarction

By

These data may be useful to clinicians in considering the risks and benefits of prescribing haloperidol for patients with cardiac morbidity.

Exploring Brain Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia

Exploring Brain Stimulation as a Treatment for Auditory Hallucinations in Schizophrenia

By

The authors pointed to a possible difference in the specific symptoms alleviated by different types of stimulation.

Recovery From First-Episode Psychosis More Likely in Those With Mania, Brief Psychosis Diagnoses

Recovery From First-Episode Psychosis More Likely in Those With Mania, Brief Psychosis Diagnoses

By

The early sustained recovery group was more likely to have a diagnosis other than schizophrenia, particularly mania or brief psychosis.

Negative Symptoms Increase Cardiovascular Risk in Schizophrenia

Negative Symptoms Increase Cardiovascular Risk in Schizophrenia

By

Although various clinical and psychosocial factors were associated with unhealthy lifestyle factors and higher risk for CVD, the strongest associations were with negative symptoms.

Improving Performance of Everyday Activities Is Critical in Schizophrenia

Improving Performance of Everyday Activities Is Critical in Schizophrenia

By

Treatment beyond antipsychotic drugs is needed for people with schizophrenia, as positive symptoms are a peripheral node in the network.

Adjunctive Raloxifene May Improve Psychotic Symptoms in Postmenopausal Women With Schizophrenia

Adjunctive Raloxifene May Improve Psychotic Symptoms in Postmenopausal Women With Schizophrenia

By

The meta-analysis showed raloxifene to be effective for positive symptoms, negative symptoms, and general psychopathology, with greatly homogeneous results.

Plasma Autoantibodies Possible Biomarker for Schizophrenia

Plasma Autoantibodies Possible Biomarker for Schizophrenia

By

Investigators selected 15 genes associated with schizophrenia due to high expression in both brain tissue and B-lymphocyte cells.

Virtual Reality Can Reduce Anxiety, Improve Social Interactions in Psychosis

Virtual Reality Can Reduce Anxiety, Improve Social Interactions in Psychosis

By

Use of virtual reality environments in which participants interact with computer-controlled situations or avatars enables a more fine-tuned approach to exposure in the context of cognitive behavioral therapy.

Psychosis Associated With Increased Complications Following Total Joint Arthroplasty

Psychosis Associated With Increased Complications Following Total Joint Arthroplasty

By

Investigators seek the association between psychosis and complication risk after total joint arthroplasty.

Suppression of Auditory Stimuli Associated With Pathologic Symptoms of Schizophrenia

Suppression of Auditory Stimuli Associated With Pathologic Symptoms of Schizophrenia

By

P50 processing may inform researchers in the future development of interventions targeting cognitive impairment in schizophrenia.

FDA Issues Refusal to File Letter in Response to New Schizophrenia Drug

FDA Issues Refusal to File Letter in Response to New Schizophrenia Drug

By

The FDA issued a refusal to file letter for a new drug application.

Why Do Antipsychotics Cause Weight Gain?

Why Do Antipsychotics Cause Weight Gain?

Researchers from the University of Texas Southwestern Medical Center have discovered the cellular receptor that causes weight gain from antipsychotic drugs.

Shared Decision Making in Psychiatry:  An Effective Practice Strategy

Shared Decision Making in Psychiatry: An Effective Practice Strategy

By

Shared decision making encourages a clinical partnership that can result in optimal treatment outcomes.

Increases in Autonomic Function May Predict Auditory Hallucinations in SCZ

Increases in Autonomic Function May Predict Auditory Hallucinations in SCZ

By

Increases in autonomic function may predict the occurrence and severity of auditory hallucinations in patients with schizophrenia, suggesting a regulation of these experiences by the autonomic nervous system.

FDA Approves New Schizophrenia Treatment for Adolescents

FDA Approves New Schizophrenia Treatment for Adolescents

By

The FDA has approved a new treatment for adolescents between the ages of 13 and 17 years who are diagnosed with schizophrenia.

Factors Predicting Favorable Outcomes in First-Episode Psychosis Without Medication

Factors Predicting Favorable Outcomes in First-Episode Psychosis Without Medication

By

Researchers profiled which young people may do well after first-episode psychosis without medication.

Low-Dose Metformin May Reduce Body Weight and BMI in Clozapine-Treated Schizophrenia

Low-Dose Metformin May Reduce Body Weight and BMI in Clozapine-Treated Schizophrenia

By

These study results indicate that early intervention with low doses of metformin in patients with few metabolic abnormalities may be beneficial.

Facial Affect Recognition Training Improves Social Outcomes in Psychosis

Facial Affect Recognition Training Improves Social Outcomes in Psychosis

By

Inability to interpret facial expressions may exacerbate psychotic symptoms, either indirectly via social defeat or directly by creating confusing interpersonal experiences.

No Difference Between Omega-3 & Placebo in Patients at Ultrahigh Risk for Psychosis

No Difference Between Omega-3 & Placebo in Patients at Ultrahigh Risk for Psychosis

By

PUFA supplementation offers little additional aid to psychosis when good psychosocial care is already sought.

Gene Expression Patterns in Polygenic Schizophrenia Risk

Gene Expression Patterns in Polygenic Schizophrenia Risk

By

Data indicate that 693 genes are differentially expressed between individuals diagnosed with schizophrenia and typical, healthy controls.

Haloperidol in the Emergency Department Setting

Haloperidol in the Emergency Department Setting

By

Dr. Scott Zeller suggests it is time to move away from emergency intramuscular haloperidol.

Effort Allocation Influences Upon Cognition in Schizophrenia

Effort Allocation Influences Upon Cognition in Schizophrenia

By

Researchers studied social cognition and social problem solving in patients with schizophrenia by employing a validated test designed to assess emotion recognition abilities.

Delusions in Schizophrenia Associated With Myelin Abnormalities, Neuroinflammation

Delusions in Schizophrenia Associated With Myelin Abnormalities, Neuroinflammation

By

Study provides further evidence for the effects of white matter fiber abnormalities and neuroinflammation on positive symptoms in patients with schizophrenia.

White Matter Abnormalities and Clinical Symptom Severity in Schizophrenia

White Matter Abnormalities and Clinical Symptom Severity in Schizophrenia

By

New findings provide an insight about the association between white matter microstructure and the severity of schizophrenia clinical symptoms.

Interaction of Proline and COMT Genotype Influences Negative Symptoms in Schizophrenia & Bipolar Disorder

Interaction of Proline and COMT Genotype Influences Negative Symptoms in Schizophrenia & Bipolar Disorder

By

The authors explored whether valproate (VPA) treatment effects vary by catechol-O-methyltransferase (COMT) genotype.

mPFC Abnormalities Associated With Social Cognition Deficits in Schizophrenia

mPFC Abnormalities Associated With Social Cognition Deficits in Schizophrenia

By

Poor psychosocial functioning among individuals diagnosed with schizophrenia is associated with deficits in social cognition.

Neuroinflammation in Schizophrenia: New PET Brain Imaging Studies

Neuroinflammation in Schizophrenia: New PET Brain Imaging Studies

By

TSPO expression is frequently used as a biomarker for brain inflammation during PET imaging.

Sign Up for Free e-newsletters