Generic Name and Formulations:
Measles, mumps, rubella, and varicella viruses live, attenuated; lyophilized pwd for SC inj after reconstitution; contains neomycin (trace), human albumin; preservative-free.
Merck & Co., Inc.
Indications for PROQUAD:
Measles, mumps, rubella, and varicella immunization; may be used if a 2nd dose of measles, mumps, rubella, and varicella vaccine is needed.
Give SC in deltoid area or upper anterolateral thigh. <12 months or ≥13yrs: not recommended. 12 months–12yrs: 1 dose of 0.5mL. If a 2nd dose is needed, give at 4–6yrs.
Egg, gelatin, or neomycin hypersensitivity. Blood dyscrasias. Leukemia, lymphoma, or other bone marrow or lymphatic malignancy. Primary or acquired immunodeficiency. Family history of congenital or hereditary immunodeficiency. Immunosuppressant therapy. Active untreated tuberculosis. Fever >101.3°F. Pregnancy (Cat.X); avoid pregnancy for 3 months after vaccination.
Have epinephrine inj (1:1000) available. History of febrile convulsions or cerebral injury. Thrombocytopenia. Avoid contact with high-risk individuals susceptible to varicella for 6 weeks after vaccination. Post-exposure prophylaxis for measles, mumps, rubella, or varicella. HIV-infected children. Contains albumin; monitor for possible infection transmission (eg, viruses, Creutzfeldt-Jakob disease). Nursing mothers: not recommended.
Immunosuppressants (see Contraindications). Avoid salicylates for 6 weeks after vaccination. Defer vaccination for at least 3 months after blood or plasma transfusions or immune globulins. Avoid immune globulin administration for 1 month after vaccination. Separate dosing of measles-containing vaccine by 1 month. If 2nd dose of varicella-containing vaccine needed, separate by 3 months. Concomitant other vaccines: see full labeling. May interfere with tuberculin skin test.
Inj site reactions, fever, irritability, rash; others.
Report adverse events to VAERS by calling (800) 822-7967.
Single-dose vials—10 (w. diluent)
Sign Up for Free e-newsletters
Psychiatry Advisor Articles
- Adjunctive Therapies for Bipolar Disorder Show Promise, Need More Evidence
- Improving Performance of Everyday Activities Is Critical in Schizophrenia
- Analysis Finds Lithium Maintenance Most Effective as Monotherapy in Bipolar Disorder
- Web-Based Intervention Targets Parental Behaviors That May Affect Adolescent Anxiety, Depression
- Abnormalities of Cortical Thickness in Bipolar Disorder With Auditory Hallucinations
- The Way to the Head May Be Through the Gut: Probiotics for Depression
- Suicide-Screening Toolkit Can Help Identify Youths at High Risk for Suicide
- Agoraphobia: An Evolving Understanding of Definitions and Treatment
- Parental Pressure to Diet Linked With Long-term Harm in Adolescents
- Does Access to Medical Cannabis Reduce Risk for Opioid Abuse?
- Mortality Rates for Substance Use Disorders, Intentional Injuries Vary Widely By Country
- Facial Emotion Recognition Differentiates Behavioral Variant Frontotemporal Dementia From MDD
- The Challenge of Helping Uninsured Patients While Protecting Practice Finances
- Antidepressants Increase Seizure Risk in Youth and Severely Depressed
- Examining Associations Between Diabetes and Effects on Cognition