Parkinson Disease

Mortality Rates in Parkinson Disease Psychosis With Pimavanserin, Quetiapine

Mortality Rates in Parkinson Disease Psychosis With Pimavanserin, Quetiapine

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In patients with Parkinson disease psychosis, treatment with pimavanserin has a lower risk for mortality compared with quetiapine or combination therapy.

Anxiety Increases Freezing of Gait Severity in Individuals With Parkinson Disease

Anxiety Increases Freezing of Gait Severity in Individuals With Parkinson Disease

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The authors suggest that anxiety should be routinely evaluated in patients with Parkinson disease who experience freezing of gait.

Cognitive Impairment Profiles Differ Between Parkinson Disease and Alzheimer Disease

Cognitive Impairment Profiles Differ Between Parkinson Disease and Alzheimer Disease

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As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.

Visual Hallucinations in Dementia and Parkinson Disease: Assessment of Patient Experiences

Visual Hallucinations in Dementia and Parkinson Disease: Assessment of Patient Experiences

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Patients who felt the situation was "abnormal" were less likely to seek help. This trend was more common in patients with Parkinson disease than patients with dementia, although both described feeling "embarrassed or ashamed."

FDA Approves New Nuplazid Formulation, Dosage Strength

FDA Approves New Nuplazid Formulation, Dosage Strength

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Nuplazid, a non-dopaminergic, selective serotonin inverse agonist, targets 5-HT2A receptors that are thought to be involved in Parkinson disease psychosis.

Acadia Addresses Concerns Over Nuplazid Safety in Parkinson Disease Patients

Acadia Addresses Concerns Over Nuplazid Safety in Parkinson Disease Patients

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Concerns over Nuplazid were initially voiced in a CNN article in early April which reported that the drug had been associated with over 700 deaths since its launch in March 2017.

Mild TBI May Increase Risk for Parkinson Disease

Mild TBI May Increase Risk for Parkinson Disease

Mild traumatic brain injury is associated with increased risk of Parkinson disease among military veterans.

Cognitive Decline in Parkinson's Disease Accurately Predicted by Algorithm

Cognitive Decline in Parkinson's Disease Accurately Predicted by Algorithm

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A new analytic model can now predict cognitive decline within 10 years of onset PD.

NfL Biomarker Assists With Parkinsonian Disorder Differentiation

NfL Biomarker Assists With Parkinsonian Disorder Differentiation

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More specific biomarkers will be needed to differentiate between atypical parkinsonian disorders.

Advancing Pain Management: Human Studies

Advancing Pain Management: Human Studies

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Research on monogenic disorders has made vital contributions to all aspects of medical care, including our understanding of pain pathophysiology.

Inhaled Levodopa for 'Off' Periods in Parkinson Disease

Inhaled Levodopa for 'Off' Periods in Parkinson Disease

Levodopa pill can wear off, but a powdered version can help patients during off periods.

Statins May Be Protective Against Parkinson's in Diabetes

Statins May Be Protective Against Parkinson's in Diabetes

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The study suggests that statins may serve a greater purpose beyond control of lipids and cardiovascular events.

Active Music Therapy May Be Beneficial in Parkinson's

Active Music Therapy May Be Beneficial in Parkinson's

Researchers saw a beneficial effect in tests examining frontal lobe function and improvement in memory.

Dopaminergic Control of Striatal Cholinergic Interneurons May Cause Antipsychotic-Associated Parkinsonism

Dopaminergic Control of Striatal Cholinergic Interneurons May Cause Antipsychotic-Associated Parkinsonism

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Research examines the underlying mechanisms for the disabling adverse effects associated with antipsychotic medications.

Urinary Biomarker of Parkinson Disease Identified

Urinary Biomarker of Parkinson Disease Identified

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To date, there are no validated biomarkers to independently assess Parkinson Disease diagnosis and prognosis, or to measure disease severity.

No Evidence for Transmission of Alzheimer Pathology Through Blood Transfusions

No Evidence for Transmission of Alzheimer Pathology Through Blood Transfusions

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If transmission of neurodegenerative diseases such as dementia of any type, AD, or PD does occur, it is rare.

Parkinson Disease Incidence On The Rise Among American Men

Parkinson Disease Incidence On The Rise Among American Men

Declining smoking rates could be associated with higher incidence of parkinsonism and PD.

FDA Approves Nuplazid for Parkinson's Disease Psychosis

FDA Approves Nuplazid for Parkinson's Disease Psychosis

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The drug is the first of its kind to address PD psychosis without having an ill effect on motor symptoms.

Physical Activity Level Affects Rate of Cognitive Decline

Physical Activity Level Affects Rate of Cognitive Decline

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Declines in processing sleep and episodic memory were observed in those with low levels of activity.

Possibly From Placebo Effect, Acupuncture Improves Fatigue in Parkinson's

Possibly From Placebo Effect, Acupuncture Improves Fatigue in Parkinson's

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The researchers observed between-group differences between real and sham acupuncture treatment.

Antipsychotics May Boost Early Death Risk in Parkinson's

Antipsychotics May Boost Early Death Risk in Parkinson's

Unclear whether the medications or the disease are the key factor; study only shows an association.

Rosacea May Increase Risk of Parkinson's

Rosacea May Increase Risk of Parkinson's

Research found an association, but no cause-and-effect relationship, between rosacea and Parkinson's.

Cognitive Decline Has Greater Impact on Speech in Parkinson's

Cognitive Decline Has Greater Impact on Speech in Parkinson's

Those with cognitive difficulties struggle to follow conversations or recall words.

Memory-Enhancing Supplements: What's the Evidence?

Memory-Enhancing Supplements: What's the Evidence?

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Study reports on the availability of safety and efficacy data for over-the-counter supplements for improving brain health.

Subjective Memory Complaints Rarely Discussed With Docs

Subjective Memory Complaints Rarely Discussed With Docs

Of adults aged 45 years and older reporting recent check-up, only 25.2% reported SMCs.

Physical Therapy May Not Help Parkinson's Patients

Physical Therapy May Not Help Parkinson's Patients

However, results should be interpreted with attention to the study details, Mayo doc says.

Lower Risk of Parkinson's In Men With Higher Uric Acid Concentration

Lower Risk of Parkinson's In Men With Higher Uric Acid Concentration

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Men with higher urate concentrations had a lower future risk of developing Parkinson's, suggesting that urate could have a protective factor.

Dementia Med Lowers Risk of Falls in Parkinson's Patients

Dementia Med Lowers Risk of Falls in Parkinson's Patients

Those who took rivastigmine in study were 45% less likely to have an accident.

Could Cholesterol-Lowering Drug Simvastatin Treat Parkinson's?

Could Cholesterol-Lowering Drug Simvastatin Treat Parkinson's?

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Results from a recent multiple sclerosis trial with simvastatin indicate that it could be an effective treatment to slow progression of Parkinson's.

Anticholinergic Drugs Not Harmful to Parkinson's Patients

Anticholinergic Drugs Not Harmful to Parkinson's Patients

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There was no difference in cognition between Parkinson's patients taking a high and lower level of anticholinergic medications.

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