Opioid-Related Disorder

Depression May Partially Mediate the Relationship Between PTSD and Opioid Misuse

Depression May Partially Mediate the Relationship Between PTSD and Opioid Misuse

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Depression may partially mediate the association between post-traumatic stress disorder and opioid misuse.

Naloxone Rarely Administered by Layperson in Opioid Deaths

Naloxone Rarely Administered by Layperson in Opioid Deaths

From July 2016 to June 2017, bystanders were documented in 44% of opioid overdose deaths, but naloxone was rarely administered by a layperson.

FDA Approves New Treatment for Opioid Dependence

FDA Approves New Treatment for Opioid Dependence

Cassipa, a film designed to be placed under the tongue, has been approved to treat opioid dependence, the US FDA said in a news release.

Oxycontin's Maker Now Selling Drug to Curb Opioid Addiction

Oxycontin's Maker Now Selling Drug to Curb Opioid Addiction

Purdue Pharma, the maker of Oxycontin who some have blamed for the epidemic of opioid painkiller addictions, has patented a medicine aimed at curbing those disorders.

Does Robust Documentation Decrease Opioid Prescribing Rates?

Does Robust Documentation Decrease Opioid Prescribing Rates?

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Accurate, transparent documentation is key in ensuring safe and appropriate opioid prescribing.

Risk Factors for Prescription Opioid Misuse Include Suicide Ideation, Past Substance Abuse Disorders

Risk Factors for Prescription Opioid Misuse Include Suicide Ideation, Past Substance Abuse Disorders

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These data underscore the impact of comorbid health conditions on opioid misuse disorders and support the use of screening for co-occurring health conditions for patients who misuse prescription opioids.

ED Plays Critical Role in Caring for Patients With Opioid Use Disorder

ED Plays Critical Role in Caring for Patients With Opioid Use Disorder

Emergency department providers need evidence-based strategies to identify and manage patients with opioid use disorder.

FDA Outlines Plan for New Analgesic Guidance to Combat Opioid Crisis

FDA Outlines Plan for New Analgesic Guidance to Combat Opioid Crisis

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The new plan will break out the current guidance into 4 separate guidances.

Prescription Drug Monitoring Program May Not Cut Opioid Use

Prescription Drug Monitoring Program May Not Cut Opioid Use

Implementation of a mandatory PDMP does not necessarily reduce the overall rate of opioid prescribing or the mean number of pills prescribed for patients undergoing general surgical procedures.

DEA Proposal Will Significantly Cut Opioid Manufacturing in 2019

DEA Proposal Will Significantly Cut Opioid Manufacturing in 2019

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Last year, the DEA proposed a 20% reduction in the manufacturing of controlled substances for 2018 compared to 2017.

Health Professionals Have Role in Warning About Impaired Driving

Health Professionals Have Role in Warning About Impaired Driving

Physicians play an important role in educating individuals about the risks of impaired driving caused by marijuana or opioids.

Opioid Dependence More Common Before Spine Surgery

Opioid Dependence More Common Before Spine Surgery

Opioid dependence is more likely to occur in patients with degenerative spondylolisthesis before surgery than afterward.

The Opioid Crisis: District by District

The Opioid Crisis: District by District

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Southern states have the 10 highest opioid prescribing rates in the country, while California, New York, and Virginia are among the bottom 10.

Opioid Administration, Prescribing in the ED on the Decline in Recent Years

Opioid Administration, Prescribing in the ED on the Decline in Recent Years

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After a rise in the frequency of opioids prescribed in emergency departments from 2005 to 2011, a decline was observed from 2012 to 2015, particularly in the 18- to 64-year age group.

Set of Personality Traits May Predict Prescription Drug Use, Misuse in Young Adults

Set of Personality Traits May Predict Prescription Drug Use, Misuse in Young Adults

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Personality traits such as anxiety sensitivity, hopelessness, sensation seeking, and impulsivity may be predictors of use and misuse of prescription drugs in young adults.

Abuse-Deterrent Opioid Formulations: Barriers to Broader Use

Abuse-Deterrent Opioid Formulations: Barriers to Broader Use

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Abuse-deterrent opioid formulations have not yet been widely accepted despite their proposed value in reducing opioid abuse and related mortality. Many of the current barriers to broader use are related to their higher cost compared with conventional formulations.

Outpatient Opioid Prescriptions for Children Often Filled

Outpatient Opioid Prescriptions for Children Often Filled

Children often fill outpatient opioid prescriptions, with the most common indication for dental procedures.

Drug treatment associated with a significant reduction in death risk following opioid overdose

Buprenorphine and methadone maintenance treatment was associated with reduced death in opioid users. No significant associations were found between naltrexone and all-cause mortality or opioid-related mortality.

US Surgeon General Urges More Americans to Carry Naloxone

US Surgeon General Urges More Americans to Carry Naloxone

The US Surgeon General released an advisory urging increased availability of the opioid overdose-reversing drug naloxone earlier this year.

NIH Initiative Aims to Address Opioid Misuse Over Long Term

NIH Initiative Aims to Address Opioid Misuse Over Long Term

A novel, innovative initiative is being developed to help end addiction over the long term.

Rate of Death Up in Year After Nonfatal Opioid Overdose

Rate of Death Up in Year After Nonfatal Opioid Overdose

There is a marked excess of deaths among US adults who experience a nonfatal opioid overdose.

Storage and Disposal Information on Opioid Package Inserts Insufficient

Storage and Disposal Information on Opioid Package Inserts Insufficient

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Oxycodone and morphine are more likely to contain messaging on package inserts describing safe storage and disposal methods compared with other commonly used and misused opioid analgesics.

Physicians should look for misuse patterns that lead to overdose before prescribing opioids

Patterns associated with opioid overdose include overlapping prescriptions, use of more than one prescriber or pharmacy, and use of out-of-state prescribers or pharmacies.

Factors Identified for Persistent Opioid Use After Pediatric Surgery

Factors Identified for Persistent Opioid Use After Pediatric Surgery

Higher daily average inpatient pain scores and higher postoperative opioid consumption are associated with a subsequent persistent opioid use.

Illicit Opioid Trade Up With Restrictions on Hydrocodone

Illicit Opioid Trade Up With Restrictions on Hydrocodone

The US Drug Enforcement Administration's 2014 ruling to reschedule hydrocodone combination products coincided with an increase in illicit trading of opioids through online illicit markets.

Wearable Device Cleared for Use During Opioid Detoxification

Wearable Device Cleared for Use During Opioid Detoxification

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Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.

FDA Warns Websites Marketing Unapproved Opioids

FDA Warns Websites Marketing Unapproved Opioids

Nine online networks, operating 53 websites, have been warned that they must stop illegally marketing potentially dangerous versions of opioid medications.

Association Between Industry Payments and Opioid Prescribing

Association Between Industry Payments and Opioid Prescribing

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Non-research industry payments to physicians may be associated with increases in opioid prescribing rates.

FDA Issues Warning to Companies Selling Kratom-Containing Products

FDA Issues Warning to Companies Selling Kratom-Containing Products

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The US Food and Drug Administration has issued warnings to 3 companies selling kratom-containing products with unsubstantiated claims regarding their effectiveness in conditions that include opioid withdrawal and addiction and chronic pain.

Court-Mandated Substance Abuse Treatment: Exploring the Ethics and Efficacy

Court-Mandated Substance Abuse Treatment: Exploring the Ethics and Efficacy

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While many treatments for substance use disorder are not evidence based, several evidence-based approaches have shown effectiveness in court-mandated treatment settings.

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