Depression may partially mediate the association between post-traumatic stress disorder and opioid misuse.
From July 2016 to June 2017, bystanders were documented in 44% of opioid overdose deaths, but naloxone was rarely administered by a layperson.
Cassipa, a film designed to be placed under the tongue, has been approved to treat opioid dependence, the US FDA said in a news release.
Purdue Pharma, the maker of Oxycontin who some have blamed for the epidemic of opioid painkiller addictions, has patented a medicine aimed at curbing those disorders.
Accurate, transparent documentation is key in ensuring safe and appropriate opioid prescribing.
Risk Factors for Prescription Opioid Misuse Include Suicide Ideation, Past Substance Abuse DisordersSeptember 10, 2018
These data underscore the impact of comorbid health conditions on opioid misuse disorders and support the use of screening for co-occurring health conditions for patients who misuse prescription opioids.
Emergency department providers need evidence-based strategies to identify and manage patients with opioid use disorder.
The new plan will break out the current guidance into 4 separate guidances.
Implementation of a mandatory PDMP does not necessarily reduce the overall rate of opioid prescribing or the mean number of pills prescribed for patients undergoing general surgical procedures.
Last year, the DEA proposed a 20% reduction in the manufacturing of controlled substances for 2018 compared to 2017.
Physicians play an important role in educating individuals about the risks of impaired driving caused by marijuana or opioids.
Opioid dependence is more likely to occur in patients with degenerative spondylolisthesis before surgery than afterward.
Southern states have the 10 highest opioid prescribing rates in the country, while California, New York, and Virginia are among the bottom 10.
After a rise in the frequency of opioids prescribed in emergency departments from 2005 to 2011, a decline was observed from 2012 to 2015, particularly in the 18- to 64-year age group.
Personality traits such as anxiety sensitivity, hopelessness, sensation seeking, and impulsivity may be predictors of use and misuse of prescription drugs in young adults.
Abuse-deterrent opioid formulations have not yet been widely accepted despite their proposed value in reducing opioid abuse and related mortality. Many of the current barriers to broader use are related to their higher cost compared with conventional formulations.
Children often fill outpatient opioid prescriptions, with the most common indication for dental procedures.
Buprenorphine and methadone maintenance treatment was associated with reduced death in opioid users. No significant associations were found between naltrexone and all-cause mortality or opioid-related mortality.
The US Surgeon General released an advisory urging increased availability of the opioid overdose-reversing drug naloxone earlier this year.
A novel, innovative initiative is being developed to help end addiction over the long term.
There is a marked excess of deaths among US adults who experience a nonfatal opioid overdose.
Oxycodone and morphine are more likely to contain messaging on package inserts describing safe storage and disposal methods compared with other commonly used and misused opioid analgesics.
Patterns associated with opioid overdose include overlapping prescriptions, use of more than one prescriber or pharmacy, and use of out-of-state prescribers or pharmacies.
Higher daily average inpatient pain scores and higher postoperative opioid consumption are associated with a subsequent persistent opioid use.
The US Drug Enforcement Administration's 2014 ruling to reschedule hydrocodone combination products coincided with an increase in illicit trading of opioids through online illicit markets.
Electrical pulses are sent through small needles that are inserted in the ear to combat the early stages of detoxification, leading to stabilization.
Nine online networks, operating 53 websites, have been warned that they must stop illegally marketing potentially dangerous versions of opioid medications.
Non-research industry payments to physicians may be associated with increases in opioid prescribing rates.
The US Food and Drug Administration has issued warnings to 3 companies selling kratom-containing products with unsubstantiated claims regarding their effectiveness in conditions that include opioid withdrawal and addiction and chronic pain.
While many treatments for substance use disorder are not evidence based, several evidence-based approaches have shown effectiveness in court-mandated treatment settings.
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