Neurocognitive

Effects of Depressive Symptoms on Cognition, Markers of Brain Aging

Effects of Depressive Symptoms on Cognition, Markers of Brain Aging

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These findings suggest a strong association between greater depressive symptoms and markers of brain aging as well as impaired episodic memory.

Clinically Significant Anxiety Tied to Subsequent Dementia Risk

Clinically Significant Anxiety Tied to Subsequent Dementia Risk

These findings indicate that anxiety may be a risk factor for late-life dementia, excluding anxiety that is related to prodromal cognitive decline.

Mortality in Alzheimer Disease Not Strongly Associated With Antipsychotics

Mortality in Alzheimer Disease Not Strongly Associated With Antipsychotics

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These results suggest that antipsychotic exposure has no impact on relative mortality.

Acadia Addresses Concerns Over Nuplazid Safety in Parkinson Disease Patients

Acadia Addresses Concerns Over Nuplazid Safety in Parkinson Disease Patients

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Concerns over Nuplazid were initially voiced in a CNN article in early April which reported that the drug had been associated with over 700 deaths since its launch in March 2017.

Mild TBI May Increase Risk for Parkinson Disease

Mild TBI May Increase Risk for Parkinson Disease

Mild traumatic brain injury is associated with increased risk of Parkinson disease among military veterans.

Traumatic Brain Injury Associated With Increased Risk for Dementia

Traumatic Brain Injury Associated With Increased Risk for Dementia

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These data support the importance of TBI preventative measures and proper management strategies for subsequent dementia.

Isolated vomiting not linked to clinically important TBI in children

Isolated vomiting (vomiting without other predictors of traumatic brain injury [TBI] as defined by 3 high-quality clinical decision rules) was not associated with clinically important TBI or evidence of TBI on computed tomography scans among pediatric patients with head injury.

Apathy Associated With Lower Health-Related Quality of Life in Huntington Disease

Apathy Associated With Lower Health-Related Quality of Life in Huntington Disease

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These data confirm the debilitating effects of apathy on functioning in patients with Huntington disease.

Apathy: An Important Predictor of Employment in Huntington Disease

Apathy: An Important Predictor of Employment in Huntington Disease

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The authors noted that apathy is very common and progressive among Huntington disease mutation carriers, even during early stages of the disease, and has been associated with decline in general functioning.

Electrical Stimulation of Amygdala May Improve Long-term Memory

Electrical Stimulation of Amygdala May Improve Long-term Memory

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Electrical stimulation of the amygdala may boost declarative memory without influencing an emotional response.

Low Opioid Use in Veterans With Recent Traumatic Brain Injury

Low Opioid Use in Veterans With Recent Traumatic Brain Injury

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Veterans diagnosed with TBI don't use opioids very often.

Cerebrovascular Dysfunction May Affect Cognition in Primary Hyperparathyroidism

Cerebrovascular Dysfunction May Affect Cognition in Primary Hyperparathyroidism

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Primary hyperparathyroidism may be linked to lower intracerebral vasomotor reactivity, which could lead to cognitive dysfunction.

Addressing Gender Disparities in Concussion Diagnosis and Treatment

Addressing Gender Disparities in Concussion Diagnosis and Treatment

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Compared with male athletes, female athletes face a greater incidence of and longer recovery time from concussion.

Cognitive Dysfunction Evaluated by fMRI in Non-Neuropsychiatric SLE

Cognitive Dysfunction Evaluated by fMRI in Non-Neuropsychiatric SLE

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Functional MRI imaging found that in patients with non-neuropsychiatric systemic lupus erythematosus, defects in spatial working memory and cognitive dysfunction were related to damage in specific neural networks.

Neural Entrainment Through Visual, Auditory Stimulation Reduces Pain Perception

Neural Entrainment Through Visual, Auditory Stimulation Reduces Pain Perception

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Patients in the visual arm of the study wore flashing LED goggles delivering visual stimulation in the alpha-band range.

Cognitive Processes' Influence on Pain Perception

Cognitive Processes' Influence on Pain Perception

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Evidence indicates that distraction can provide pain relief, highlighting the influence cognitive processes have on pain perception.

Midlife Hypertension and Late-life Neurocognitive Status

Midlife Hypertension and Late-life Neurocognitive Status

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The American Heart Association issues a scientific statement on the possible link between chronic arterial hypertension and cognitive impairment.

Late-life Volunteering Helps Maintain Cognitive Function

Late-life Volunteering Helps Maintain Cognitive Function

Regular late-life volunteering is independently tied to decreased risk of cognitive impairment.

Is There a Link Between Midlife Hypertension and Late-life Cognitive Dysfunction

Is There a Link Between Midlife Hypertension and Late-life Cognitive Dysfunction

The American Heart Association issues a scientific statement on the possible link between chronic arterial hypertension and cognition.

Ambiguity Aversion is Attenuated in Schizophrenia

Ambiguity Aversion is Attenuated in Schizophrenia

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Researchers conducted an fMRI study of decision-making under conditions of risk and ambiguity in patients diagnosed with schizophrenia.

Gender-dependent Differences in Alzheimer Disease Diagnosis

Gender-dependent Differences in Alzheimer Disease Diagnosis

In 2016, an estimated 5.4 million US adults have Alzheimer disease.

T2D and Cognition: Role of Ghrelin System

T2D and Cognition: Role of Ghrelin System

Serum ghrelin levels may serve as a biomarker of executive function in patients with type 2 diabetes.

Sundowning: Phenomenology, Pathophysiology, and Treatment Approaches

Sundowning: Phenomenology, Pathophysiology, and Treatment Approaches

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Sundowning is a complex multifactorial condition that has eluded rigorous understanding of its pathophysiological causes.

Cognition in Depression: A Critical Domain for Health Outcomes, Measurement, and Treatment

Cognition in Depression: A Critical Domain for Health Outcomes, Measurement, and Treatment

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Dr. Roger McIntyre suggests that the clinical relevance of cognitive dysfunction for any individual patient can only be adjudicated on a case-by-case basis.

Does Impaired Cognition Precede Depression?

Does Impaired Cognition Precede Depression?

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Dysfunction across several cognitive domains is often concomitant with depression.

Investigating Superagers' Neuroanatomy, Memory Abilities

Investigating Superagers' Neuroanatomy, Memory Abilities

Most aging humans will develop some degree of decline in cognitive capacity.

mPFC Abnormalities Associated With Social Cognition Deficits in Schizophrenia

mPFC Abnormalities Associated With Social Cognition Deficits in Schizophrenia

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Poor psychosocial functioning among individuals diagnosed with schizophrenia is associated with deficits in social cognition.

Alcohol Consumption and Alzheimer Disease: A Brief Update

Alcohol Consumption and Alzheimer Disease: A Brief Update

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Basic Research Findings for the Practicing Clinician

Anxiety is a Risk Factor for Cognitive Decline and Dementia

Anxiety is a Risk Factor for Cognitive Decline and Dementia

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Most research to date has focused on the association between depression and dementia, but not many studies were performed to investigate the link between anxiety and dementia.

A Successful Approach to Reduce Phobic Behavior

A Successful Approach to Reduce Phobic Behavior

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Investigators used fMRI to examine whether disruption of long-term fear memory reconsolidation can attenuate the activity in the amygdala at re-exposure to fear cues.

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