Mood Disorders

Symptom Improvement Seen With Interpersonal Psychotherapy, Sertraline in Postpartum Women

Symptom Improvement Seen With Interpersonal Psychotherapy, Sertraline in Postpartum Women

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Investigators examined the efficacy of sertraline and interpersonal psychotherapy vs pill placebo over 12 weeks in woman with postpartum depression.

For Teen Girls, Depression May Predict Subsequent Alcohol Use

For Teen Girls, Depression May Predict Subsequent Alcohol Use

For adolescent girls, depression, but not anxiety, predicts future alcohol use.

KCNQ Channel Potentiator Ezogabine Delivers Promising Results in Major Depressive Disorder

KCNQ Channel Potentiator Ezogabine Delivers Promising Results in Major Depressive Disorder

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The use of ezogabine, a KCNQ channel opener, may improve depression and anhedonic symptoms in patients with major depressive disorder.

Genetic Analysis Shows Higher BMI May Increase Risk for Depression

Genetic Analysis Shows Higher BMI May Increase Risk for Depression

Findings based on large study assessing genetic causal link, even without metabolic effects

Effects of Mindfulness Meditation on Mood in Middle-Age, Older Adults

Effects of Mindfulness Meditation on Mood in Middle-Age, Older Adults

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Mindfulness meditation training may reduce negative affect variability in middle-age and older adults.

Effects of Impaired Glucose Metabolism on Lithium and Other Mood Stabilizers

Effects of Impaired Glucose Metabolism on Lithium and Other Mood Stabilizers

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High blood sugar levels may put patients with bipolar disorder at risk of not responding to lithium and other mood stabilizer treatments.

Serum Uric Acid May Predict Bipolar Disorder in Patients With Depression

Serum Uric Acid May Predict Bipolar Disorder in Patients With Depression

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Investigators examined whether high serum uric acid is a risk biomarker for conversion of major depressive disorder to bipolar disorder.

Screening Tool May Identify Distress in Parents of Children With Chronic Pain

Screening Tool May Identify Distress in Parents of Children With Chronic Pain

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A self-report screening tool designed to identify impaired psychosocial functioning and behavioral responses in parents of children with chronic pain was found to be useful clinically.

Inflammation Associated With Gray Matter, Hippocampal Volume Reduction in Older Adults With Bipolar Disorder

Inflammation Associated With Gray Matter, Hippocampal Volume Reduction in Older Adults With Bipolar Disorder

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Inflammation appears to be associated with reductions in hippocampal and gray matter volumes in older patients with bipolar I disorder.

FDA Panel Votes on Postpartum Depression Treatment Zulresso

FDA Panel Votes on Postpartum Depression Treatment Zulresso

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If approved, Zulresso would be the first drug approve for the treatment of postpartum depression.

Mood Stabilizers Associated With Increased Risk for Stroke in Bipolar Disorder

Mood Stabilizers Associated With Increased Risk for Stroke in Bipolar Disorder

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Exposure to carbamazepine was associated with the highest risk for stroke, particularly ischemic stroke.

Postpartum Pain Associated With Increased Risk for Postpartum Depression

Postpartum Pain Associated With Increased Risk for Postpartum Depression

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Patients at high risk for postpartum depression may need denser analgesia control after delivery.

Customized Adherence Enhancement Intervention Improves Adherence Rates in Bipolar Disorder

Customized Adherence Enhancement Intervention Improves Adherence Rates in Bipolar Disorder

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Customized adherence enhancement may be most effective if implemented in individuals early in the course of bipolar disorder.

FDA Committees Vote on Opioid System Modulator for MDD Treatment

FDA Committees Vote on Opioid System Modulator for MDD Treatment

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In the meeting documents, the panel presented a scenario which illustrated their concerns regarding potentially complex drug interactions that may occur in the population for which the drug is intended.

Meta-Analysis: Do Electroencephalographic Biomarkers Predict Treatment Response in Depression?

Meta-Analysis: Do Electroencephalographic Biomarkers Predict Treatment Response in Depression?

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The meta-analysis consisted of a review of 53 articles covering 57 distinct biomarkers.

Education, Inflammation Predict Cognitive Performance in Bipolar Disorder

Education, Inflammation Predict Cognitive Performance in Bipolar Disorder

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Researchers set out to examine how bipolar disorder affects cognitive performance across a variety of clinical parameters.

High-Activity Temperaments Appear to Be Protective of Major Mood Episodes in Offspring at High Genetic Risk

High-Activity Temperaments Appear to Be Protective of Major Mood Episodes in Offspring at High Genetic Risk

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After a major depressive episode, sociability, activity, and self-esteem measures decreased, while emotionality and shyness scores increased.

Mortality Rate for Bipolar Disorder Has Increased in Denmark Since the 1990s

Mortality Rate for Bipolar Disorder Has Increased in Denmark Since the 1990s

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Younger individuals may be more at risk for death by suicide, and in older patients, elevated levels of metabolic syndrome may lead to higher rates of death from heart disease.

Psilocybin Gets Breakthrough Therapy Designation for Treatment-Resistant Depression

Psilocybin Gets Breakthrough Therapy Designation for Treatment-Resistant Depression

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Psilocybin, the active ingredient in "magic mushrooms", has been granted Breakthrough Therapy designation by the FDA for treatment-resistant depression.

Vortioxetine Beats Escitalopram in Improving SSRI-Induced Sexual Dysfunction

Vortioxetine Beats Escitalopram in Improving SSRI-Induced Sexual Dysfunction

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Takeda announced that the FDA has approved a labeling update for Trintellix to include new head-to-head clinical data comparing it to Lexapro for improving treatment-emergent sexual dysfunction.

High Burden of Depression, Anxiety Reported Among Adults With Arthritis

High Burden of Depression, Anxiety Reported Among Adults With Arthritis

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Data from the CDC show that the prevalence of anxiety and depression is higher among adults with arthritis compared with the general population.

Manic Episode Inpatient Admissions Appear to Peak During Summer

Manic Episode Inpatient Admissions Appear to Peak During Summer

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For manic episodes, admissions for men peaked in June, and in September for women.

Mental Health Problems in Adolescents With HIV: Overview & Expert Interview

Mental Health Problems in Adolescents With HIV: Overview & Expert Interview

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Adolescents infected with HIV have a greater risk for psychiatric hospitalizations compared with those not infected with HIV.

High Risk for Anxiety, Depression, and Stress Observed Among Single Mothers

High Risk for Anxiety, Depression, and Stress Observed Among Single Mothers

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This research promotes the use of more rigorous screening efforts for mental illness among single mothers.

Psychotropic Medications May Improve Pregnancy Outcomes in Bipolar Disorder

Psychotropic Medications May Improve Pregnancy Outcomes in Bipolar Disorder

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Reduced head circumference in the offspring of women with untreated bipolar disorder appeared to be related to sociodemographic characteristics.

Suicide Attempts Associated With Sleep and Circadian Rhythm Disturbances in Bipolar Disorder

Suicide Attempts Associated With Sleep and Circadian Rhythm Disturbances in Bipolar Disorder

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All patients with bipolar disorder had more circadian rhythm and sleep disturbances than healthy control patients.

Retirement Associated With Increased Risk for Depressive Symptoms

Retirement Associated With Increased Risk for Depressive Symptoms

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Employment status displayed a lagged effect on depression, with retirement preceding higher levels of depression 2 years after initial retirement status report.

Teacher, Student Psychological Well-being Linked

Teacher, Student Psychological Well-being Linked

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Educators' mental health and well-being is associated with their students' mental well-being or feelings of distress.

Early Risk Factors for Bipolar Disorder Found in Offspring of BD Parents

Early Risk Factors for Bipolar Disorder Found in Offspring of BD Parents

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The most robust predictive risk factor for BD is a confirmed history of the illness in a first-degree relative, which is associated with an 8-fold to 10-fold lifetime risk for BD and a 2-fold to 3-fold lifetime risk for depressive disorder vs the general population.

Link Identified Between Cured Meat and Mania in Bipolar Disorder

Link Identified Between Cured Meat and Mania in Bipolar Disorder

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These results suggest that the nitrates in cured meat are driving the association between cured meat consumption and mania.

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