Psoriasis May Increase Risk of Developing Depression
the Psychiatry Advisor take:
Having psoriasis may increase the risk of developing major depression.
Roger S. Ho, MD, MPH, of the New York University School of Medicine, New York, and colleagues analyzed data from the National Health and Nutrition Examination Survey between 2009 and 2012 that included 12,382 participants. They examined the relationship between the chronic inflammatory skin disease psoriasis and depression, after adjusting for cardiovascular risk.
In the study, 28% of participants were found to have psoriasis, and 7.8% had major depression. Also, 16.5% of patients with psoriasis also met criteria for major depression, the researchers reported in JAMA Dermatology.
Additional analyses indicated that the risk of depression was not different in patients with limited vs. extensive psoriasis. Also, a history of cardiovascular events did not affect the depression risk in psoriasis patients. However, more patients with psoriasis (23.6%) reported that any symptoms of depression caused daily functional impairment, compared with patients without psoriasis (15.4%).
Psoriasis impacts between 3% and 4% of the U.S. population, and the psychological impact of the condition can be severe.
“Our study supports that all patients with psoriasis, regardless of severity, are at risk for depressive symptoms and may benefit from depression screening,” the authors concluded.
The risk of depression was not different in patients with limited vs. extensive psoriasis.
The chronic inflammatory skin condition psoriasis was associated with the risk of major depression, although the risk was unrelated to the severity of the disorder, according to an article published online by JAMA Dermatology.
Psoriasis affects 3 percent to 4 percent of the U.S. population, and the psychological impact of psoriasis can be substantial. The identification of depression among patients with psoriasis is especially important because major depression is associated with decreased quality of life and increased all-cause mortality.
Roger S. Ho, MD, MS, MPH, of the New York University School of Medicine, New York, and coauthors examined the relationship between psoriasis and major depression in a nationally representative group, after adjusting for cardiovascular risk because prior research has suggested both depression and psoriasis are associated with cardiovascular disease.
Sign Up for Free e-newsletters
Psychiatry Advisor Articles
- Rapid Cycling in Bipolar Disorder: Overview and Expert Perspectives
- First-Episode Drug-Naive Patients With Schizophrenia More Likely to Attempt Suicide
- Posttraumatic Stress Disorder Associated With Reduced Brain Volume
- Early Childhood Out-of-Home Placement Associated With Adverse Outcomes in Adulthood
- ADHD Medications Compared for Efficacy, Tolerability in Children and Adults
- The Psychology of Hoarding Disorder: Approaches for Treatment
- Mind-Body Therapy and Psychiatry: Ancient Tools for Modern Practice
- Smartphone Applications for Depression and Anxiety: Are They Ready for Widespread Use?
- The Many Misconceptions of Catatonia: Treatment Is Often Successful With the Right Knowledge
- Marijuana Use Associated With Poorer Depression Outcomes, Increased Suicidal Ideation
- Symptoms of Anxiety, Depression Differ Depending on Gender, Race, Ethnicity
- Examining Whether Adjunctive Glutamatergic Medication Further Eases OCD Symptoms
- FDA Permits Marketing of Brain Stimulation Device for OCD
- Antipsychotics Adversely Affect Adiposity and Insulin Sensitivity in Youths
- Know Before You Go: Practicing Medicine Abroad