Brain Protein May Cause High Depression Rates in Perimenopause
the Psychiatry Advisor take:
Elevated levels of a specific brain protein may explain why so many women experience depression during perimenopause, according to a new study. High levels of a chemical called monoamine oxidase A, or MAO-A, may be to blame, the paper concludes.
The protein is known to break down other brain chemicals such as serotonin, norepinephrine and dopamine which help to maintain normal mood.
Rates of depression in women in perimenopause are unusually high. Previous studies have suggested that first-time depressions in women in this period of life reach 16 to 17% and a similar percentage of women develop milder depressive symptoms.
Brain protein may be cause of high rates of depression in perimenopause
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