Generic Name and Formulations:
Sodium hyaluronate 22mg/mL; viscoelastic soln for intra-articular inj.
Indications for MONOVISC:
Treatment of pain in osteoarthritis of the knee in patients who have failed to respond adequately to conservative nonpharmacologic therapy or simple analgesics (eg, acetaminophen).
Remove synovial fluid or effusion before inj. Give as a single intra-articular inj. 4mL in one knee only. If bilateral treatment: use one syringe in each knee.
≤21yrs: not established.
Gram (+) bacterial protein allergy. Infections or skin diseases in area of inj site/joint. Systemic bleeding disorders.
Avoid strenuous or prolonged weight-bearing activities within 48hrs following inj. Pregnancy, nursing mothers: not established.
Avoid use of disinfectants containing quaternary ammonium salts; hyaluronan can precipitate in their presence.
Arthralgia, joint swelling, inj site pain.
Single-use syringe (4mL)—1
Sign Up for Free e-newsletters
Psychiatry Advisor Articles
- Adjunctive Therapies for Bipolar Disorder Show Promise, Need More Evidence
- Predicting Treatment-Emergent Mania to Tailor Pharmacotherapy in Bipolar Disorder
- Abnormalities of Cortical Thickness in Bipolar Disorder With Auditory Hallucinations
- Antidepressants Increase Seizure Risk in Youth and Severely Depressed
- Prevalence of Major Depressive Disorder Remains High In US Population
- The Way to the Head May Be Through the Gut: Probiotics for Depression
- Suicide-Screening Toolkit Can Help Identify Youths at High Risk for Suicide
- Agoraphobia: An Evolving Understanding of Definitions and Treatment
- Parental Pressure to Diet Linked With Long-term Harm in Adolescents
- Does Access to Medical Cannabis Reduce Risk for Opioid Abuse?
- Evidence of Methylphenidate Abuse: Characterizing Patterns of Use in Pediatric and Adult Populations
- Intranasal Oxytocin Reduces Negative Effects, Improves Cognitive Function in Schizophrenia
- Most Patients Comfortable With Clinicians Asking About Sexual Orientation
- Peer-to-Peer Depression Awareness Program May Be Beneficial
- Examining Rates of Long-term Opioid Use in Youth With Psychiatric Disorders