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Megestrol Oral Suspension
Anorexia/cachexia
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Drug Name:

Megestrol Oral Suspension Rx

Generic Name and Formulations:
Megestrol acetate 40mg/mL; lemon-lime flavor.

Company:
Various generic manufacturers

Therapeutic Use:

Indications for Megestrol Oral Suspension:

Anorexia, cachexia, or unexplained significant weight loss in patients diagnosed with AIDS.

Adult:

Initially 800mg/day.

Children:

Not established.

Contraindications:

Pregnancy.

Warnings/Precautions:

Do not substitute with other megestrol suspensions (not interchangeable). History of thromboembolic disease. Monitor for signs/symptoms of adrenal insufficiency; consider empiric therapy if occurs. Diabetes. Renal impairment. Elderly. Fetal toxicity. Obtain (–) pregnancy test prior to initiation. Advise females of reproductive potential to use effective contraception during therapy. Nursing mothers: not recommended.

Pharmacological Class:

Progestin.

Interactions:

May increase insulin requirements. Decreases indinavir levels.

Adverse Reactions:

GI upset, impotence, flatulence, rash, hypertension, fever, decreased libido, breakthrough bleeding, hyperglycemia, insomnia.

How Supplied:

Contact supplier.

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