These data confirm the debilitating effects of apathy on functioning in patients with Huntington disease.
The authors noted that apathy is very common and progressive among Huntington disease mutation carriers, even during early stages of the disease, and has been associated with decline in general functioning.
Electrical stimulation of the amygdala may boost declarative memory without influencing an emotional response.
The HD-associated CAG repeat with 36 or more repeats was found in 18 individuals.
The FDA has accepted Teva's New Drug Application for deutetrabenazine to treat chorea associated with Huntington's disease.
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