Insomnia Research News, Treatment Studies

FDA to Review Tasimelteon for Smith-Magenis Syndrome

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The applications are supported by positive results from a double-masked, 4-week, pivotal phase 2/3 clinical trial that compared the effects of tasimelteon to placebo in 25 patients with SMS.

Placebo May Worsen First Lab Night Sleep in Patients With Insomnia

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Amit Akirov, MD

Placebo administration may worsen first lab night sleep in patients with insomnia, potentially exhibiting a nocebo effect.

Effects of Sleep Deprivation on Cortical Spreading Depolarization

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Amit Akirov, MD

Acute sleep deprivation may cause increased frequency of cortical spreading depolarization and reduce its electrical threshold.

In-Person CBT Noninferior to Telemedicine-Delivered Therapy for Insomnia

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Jessica Nye, PhD

Both in-person and telemedicine-delivered cognitive behavioral therapy are effective treatments for chronic insomnia.

Nighttime Light Exposure Contributes to Sleep Problems, Psychiatric Symptoms in Adolescents

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Emily Pond

Artificial light at night was positively associated with markers of social disadvantage, including minority status, lower family income, lower parental education, and having 1 or more first relatives born outside the US.

Cognitive behavioral therapy (CBT) may reduce the incidence of insomnia symptoms in adolescents, according to study data presented at the 2019 World Sleep Congress.

Cognitive Behavioral Therapy for Insomnia in Patients With Depression: What Works?

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Jessica Nye, PhD

Despite the negative opinion of group therapy, the patients had a general preference for nonpharmacological treatment.

Zolpidem, Behavioral Therapy Produce Comparable Reductions in Insomnia Symptoms

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Emily Pond

Among patients who did not remit with behavioral therapy, those who switched to zolpidem (40.6% to 62.7%) or cognitive therapy (50.1% to 68.2%) were more likely to respond.