Schizophrenia Spectrum and Psychotic Disorders

Major Brain Network Changes In Severe Schizophrenia

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Brain regions impacted influence the negative symptoms and social functioning associated with schizophrenia.

People who suffer from severe schizophrenia have very different brain networks compared to others with milder schizophrenia, bipolar disorder, or no mental illness, according to new research from Canada’s Centre for Addiction and Mental Health (CAMH).

Researchers say the findings confirm mounting evidence that schizophrenia is in fact more than one brain disorder.

The study involved magnetic resonance brain imaging (MRI) of 128 people with schizophrenia and 130 healthy individuals at two sites, and with 39 patients with bipolar disorder and 43 healthy individuals at a third site.

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