Length of Brain Fold Tied to Hallucinations in Schizophrenia

Some people with schizophrenia have hallucinations, which means they see, hear, smell or feel things that nobody else experiences. Now, a new study sheds light on this condition and suggests that there are differences in a key region of the brain for people with schizophrenia who have hallucinations, compared with those who do not.

The researchers — led by Dr. Jon Simons from the University of Cambridge in the UK — publish their study in the journal Nature Communications.

For quite some time, researchers have believed that an imbalance in the chemical reactions of the brain could play a role in schizophrenia.

But in a previous study, Dr. Simons and colleagues found that variations in the length of a fold toward the front of the brain — known as the paracingulate sulcus (PCS) — in healthy individuals was associated with the ability to distinguish real from imagined information, which is a process known as “reality monitoring.”

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