Inflammation in Brain Linked to Schizophrenia

A study published today in the American Journal of Psychiatry is the first to find that immune cells are more active in the brains of people at risk of schizophrenia as well as those already diagnosed with the disease.

The finding could completely change our current understanding of schizophrenia, raising the possibility that testing people most at risk of the disorder ahead of time could allow them to be treated early enough to avoid its most severe symptoms.

Researchers at the Medical Research Council’s (MRC) Clinical Sciences Centre, based at Imperial College London, in collaboration with colleagues at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King’s College London, used positron emission tomography (PET) scans to measure levels of activity of immune cells in the brain.

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