Using advanced brain imaging, researchers have matched certain behavioral symptoms of schizophrenia to features of the brain’s anatomy. The findings, at Washington University School of Medicine in St. Louis, could be a step toward improving diagnosis and treatment of schizophrenia.

The study, available online in the journal NeuroImage, will appear in print Oct. 15.

The researchers evaluated scans taken with magnetic resonance imaging (MRI) and a technique called diffusion tensor imaging in 36 healthy volunteers and 47 people with schizophrenia. The scans of patients with schizophrenia revealed various abnormalities in portions of the corpus callosum, a bundle of fibers that connects the left and right hemispheres of the brain and is considered critical to neural communication.

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