Smoking increases the metabolism of clonidine through the CYP1A2, which may require the dose to be doubled to have the same plasma concentration as a non-smoker.
Individuals with psychotic disorders have a 10 to 15 year shorter life span compared with the general population, mostly due to physical conditions like obesity, cardiovascular disease, and type 2 diabetes. A cardiometabolic risk prediction algorithm can offer informed treatment decisions in order to prevent long-term cardiometabolic outcomes.
The goal of the researchers was to describe the short- and long-term effects of brexpiprazole on Positive and Negative Syndrome Scale (PANSS) “Marder factors.”
The designation is based on results from a phase 2 trial that evaluated the efficacy and safety of 4 different doses of BI 425809 orally once daily in adults with CIAS for 12 weeks.
Researchers evaluated a case study and treatment of a patient who was diagnosed with schizophreniform disorder who presented at an emergency department testing positive for COVID-19.
