Protein That Builds Up With Age Linked to Memory Problems

Stopping the buildup of beta-2-microglobulin (B2M) protein in the blood and brain may prevent or reverse memory problems.

Researchers may have found a way to slow down or prevent memory problems that arise in old age and which can become devastating in patients with dementia.

The fresh hope comes from a series of studies in humans and mice that identified a protein which causes memory impairment when it builds up in the blood and brain with age.

Scientists found that injections of the protein made young animals’ memories worse and reduced the growth of new neurons in their brains. Further studies showed that blocking the protein prevented memory loss in older animals, making them smarter than untreated animals of the same age.

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