Mortality Rates in Parkinson Disease Psychosis With Pimavanserin, Quetiapine
In patients with Parkinson disease psychosis, treatment with pimavanserin has a lower risk for mortality compared with quetiapine or combination therapy.
Parkinson’s Disease
PARKINSON DISEASE
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Anxiety Increases Freezing of Gait Severity in Individuals With Parkinson Disease
The authors suggest that anxiety should be routinely evaluated in patients with Parkinson disease who experience freezing of gait.
Cognitive Impairment Profiles Differ Between Parkinson Disease and Alzheimer Disease
As the neurodegenerative processes of Alzheimer disease and Parkinson disease are different, early cognitive impairment also present differently in these diseases.
Visual Hallucinations in Dementia and Parkinson Disease: Assessment of Patient Experiences
Patients who felt the situation was “abnormal” were less likely to seek help. This trend was more common in patients with Parkinson disease than patients with dementia, although both described feeling “embarrassed or ashamed.”
FDA Approves New Nuplazid Formulation, Dosage Strength
Nuplazid, a non-dopaminergic, selective serotonin inverse agonist, targets 5-HT2A receptors that are thought to be involved in Parkinson disease psychosis.
Acadia Addresses Concerns Over Nuplazid Safety in Parkinson Disease Patients
Concerns over Nuplazid were initially voiced in a CNN article in early April which reported that the drug had been associated with over 700 deaths since its launch in March 2017.
Mild TBI May Increase Risk for Parkinson Disease
Mild traumatic brain injury is associated with increased risk of Parkinson disease among military veterans.
Cognitive Decline in Parkinson’s Disease Accurately Predicted by Algorithm
A new analytic model can now predict cognitive decline within 10 years of onset PD.
NfL Biomarker Assists With Parkinsonian Disorder Differentiation
More specific biomarkers will be needed to differentiate between atypical parkinsonian disorders.
Inhaled Levodopa for ‘Off’ Periods in Parkinson Disease
Levodopa pill can wear off, but a powdered version can help patients during off periods.
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