Parkinson’s Disease

Latest News

Pimavanserin Improves Comorbid Depressive Symptoms in Patients With Parkinson Disease

By

Brandon May

Pimavanserin, either alone or in conjunction with a selective serotonin reuptake inhibitor or serotonin–norepinephrine reuptake inhibitor, may improve comorbid depression symptoms in patients with Parkinson disease.

Study Author Q&A: A Novel Antipsychotic Treatment for Schizophrenia

By

Nicole Bowens, PhD

To learn more about SEP-363856 as a novel treatment for schizophrenia, we spoke with Kenneth Koblan, PhD, and John Krystal, MD.

Patients With Parkinson Disease Report Higher Prevalence of Ophthalmologic Symptoms

By

Brandon May

Compared to the general population, patients with Parkinson disease report a higher prevalence of ophthalmologic symptoms.

Efficacy of Isradipine in Early-Stage Parkinson Disease

By

Amit Akirov, MD

Researchers assessed the effect of isradipine on clinical progression in previously untreated patients with early-stage PD.

How Exercise Affects Sleep Outcomes in Parkinson Disease

By

Amit Akirov, MD

High-intensity exercise training may improve sleep parameters in patients with Parkinson disease.

Phone-Based Therapy Beneficial for Depression in Parkinson Disease

Telephone-based cognitive behavioral therapy seems to be an effective intervention for depression in Parkinson disease, outperforming treatment-as-usual on all depression, anxiety, and quality-of-life measures.

Abnormal Cerebral Blood Flow May Influence the Etiology of Parkinson Disease

By

Amit Akirov, MD

Patients with Parkinson disease tend to have an increase in iron content with reduced perfusion in the substantia nigra.

Iron Deposition Provides Cognitive Clues in Patients with Parkinson Disease

By

Alyssa Capel

Up to half of patients with Parkinson disease are also diagnosed with dementia, but tools to track changes in cognition are lacking.

Ophthalmologic Symptoms Common in Parkinson Disease

Patients with Parkinson disease have a higher prevalence of ophthalmologic symptoms than controls.

Stress-Related Disorders Linked to Neurodegenerative Disease

Stress-related disorders are associated with an increased risk for neurodegenerative diseases.