Parkinson’s Disease

Latest News

Review Explores Risk for Early-Onset Stroke, Parkinson Disease With Methamphetamine Use

By

Emily Pond

The review authors sought to elucidate the neurological harms of methamphetamine, which are well-documented but poorly understood.

Parkinson Disease-Related Brain Metabolic Patterns as Phenoconversion Biomarker

By

Rita Aghjayan

This prospective cohort study assessed whether PD-related brain metabolic patterns may be used as biomarkers in isolated REM sleep behavior disorder.

Recommendations on Weekly Exercise and Physical Activity Routines for Patients With Parkinson Disease

By

Jessica Nye, PhD

Studies have identified that patients who engage in exercise had improved symptoms of the disease in addition to higher quality of life, improved balance and mobility, fewer depressive symptoms, and improved thinking skills.

Gel Formulation of Neuroactive Drugs for Parkinson Disease Administered Intranasally May Be More Effective Delivery Method

By

Jessica Nye, PhD

The study researchers reported on a self-assembled hydrogel to deliver the drug 4-dihydroxyphenylalanine (L-DOPA) for Parkinson disease.

Long-Term Low-Dose Sargramostim Therapy Restores Immune Homeostasis in Parkinson Disease

By

Jessica Nye, PhD

Because sargramostim therapeutic use has been offset by dose-dependent adverse events, the researchers performed a reduced drug dose regimen to evaluate safety and to discover novel disease-linked biomarkers during sargramostim treatments for 1 year.

Parkinson Disease Linked to Exposure to Nitrogen Dioxide Air Pollutants

By

Jessica Nye, PhD

The researchers’ goal studied whether exposure to particulate matters, nitrogen dioxide, ozone, sulfur dioxide, or carbon monoxide raises the risk of Parkinson disease.

First-of-its-Kind Deep Brain Stimulation Directional Lead Approved

By

Brian Park, PharmD

The system works with Medtronic’s Percept™ PC Neurostimulator.

Benefits of Deep Brain Stimulation Persist in Parkinson Disease

For patients with Parkinson disease, deep brain stimulation of the subthalamic nucleus is effective beyond 15 years after implantation.

Systemic Monocyte Activation Patterns in Early Parkinson Disease Appear to Differ by Sex

By

Emily Pond

To better understand the relationship between peripheral blood monocyte activation and PD, investigators recruited a population of patients with untreated early PD.

Evaluating and Treating Respiratory Decompensation in Parkinson Disease Patients With COVID-19

By

Faisal A. Islam, MD, MBA, BCMAS

Ranbir Dhillon, MD

Zia Choudhry, MD, PhD, MBA

The unprecedented numbers of patients on mechanical ventilation underscore the severity of the coronavirus on public health. Elderly patients, especially those with Parkinson disease, often bear the brunt of the pandemic due to pre-existing pulmonary disease and/or anatomical disposition.