Nearly two-thirds of Americans with Alzheimer’s disease are women, and now some scientists are questioning the long-held assumption that it’s just because they tend to live longer than men.

What else may put women at extra risk? Could it be genetics? Biological differences in how women age? Maybe even lifestyle factors? Finding out might affect treatments or preventive care.

One worrisome hint is that research shows a notorious Alzheimer’s-related gene has a bigger impact on women than men.

A recent Alzheimer’s Association report estimates that at age 65, women have about a 1 in 6 chance of developing Alzheimer’s during the rest of their lives, compared with a 1 in 11 chance for men.

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