Neuropsychiatric Symptoms Increase Dementia Risk

Neuropsychiatric symptoms in the presence of mild cognitive impairment (MCI), including depression, appear to significantly increase the risk of conversion to dementia —either amnestic or Alzheimer’s type-dementia — according to a study released today by AJP in Advance.

Diabetes and prediabetes increased risk of conversion from amnestic MCI to Alzheimer’s dementia and from any-type or nonamnestic MCI to all-cause dementia. But the researchers also found that the presence of neuropsychiatric symptoms predicted conversion to all-cause dementia, and depressive symptoms predicted conversion from any-type MCI to all-cause dementia in epidemiological but not clinical studies.

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