Memory Decline to Dementia Pathway Clarified

Canadian scientists have made progress toward explaining how brain changes progress from mild cognitive impairment (MCI) to Alzheimer’s-type dementia.

Understanding this pathway is critical for development of therapies to address Alzheimer’s in its early stages.

In the new study, a team lead by Dr. Sylvie Belleville, Ph.D., Director of the Research Centre at Montreal Geriatric Institute and Professor of Psychology at Université de Montréal, showed the typical patterns of the brain’s progression to dementia.

Researchers compared changes that occurred over many years in people with stable MCI with changes in people for whom MCI progressed to a diagnosis of Alzheimer’s.

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