People who frequently engaged in cognitively-stimulating activities had greater volumes in key brain areas that may protect against Alzheimer’s disease-related outcomes, researchers reported here.

Stephanie Schultz, BS, from the Wisconsin Alzheimer’s Disease Research Center at the University of Wisconsin in Madison, reported that volumes of structures such as the hippocampus and posterior cingulate differed significantly between older individuals who frequently performed activities such as playing cards or checkers or doing crosswords or other puzzles and those who spent less time in these activities.

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