Aging of Brain’s Grey Matter Linked to Alzheimer’s, Schizophrenia

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Grey matter, one of the last parts of the brain to develop, is also one of the first to show signs of neurodegeneration.

New research has emerged that reveals a specific brain network — that is the last to develop and the first to show signs of neurodegeneration — is more vulnerable to unhealthy aging as well as to disorders that emerge in young people, shedding light on conditions such as Alzheimer’s disease and schizophrenia.

The team focused on grey matter in the brain,  a network of nerve cells that coordinate information from different senses.

The researchers, led by Dr. Gwenaëlle Douaud at the Oxford University Functional MRI of the Brain Centre in the UK, say their work sheds light on potential genetic and environmental factors that may occur early in life, causing lifelong consequences.

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