Alzheimer Disease and Dementia

Latest News

P-tau181 Biomarker Predicts Risk of Alzheimer Dementia

By

Brandon May

Plasma phosphorylated tau181 (P-tau181) may aid in the diagnosis of Alzheimer disease (AD), a study in Natural Medicine suggests.

Sleep-Disordered Breathing Tied to Brain Changes

Sleep-disordered breathing is associated with changes in the brain, including amyloid deposition in brain regions typically involved in Alzheimer disease.

PCPs Feel Unprepared in Providing Dementia Care

Primary care physicians believe they are on the front lines of dementia care, but many feel unprepared.

Brain Amyloid Deposition and Intracranial Atherosclerotic Disease in Adults

By

Amit Akirov, MD

There is no evidence for an association between cerebral β-amyloid deposition, a marker of Alzheimer disease, and intracranial atherosclerotic plaque or stenosis.

Higher Flavonol Intake May Protect Against Alzheimer Disease

By

Amit Akirov, MD

Higher flavonol intake through food sources, mostly fruits and vegetables, may protect against the development of Alzheimer disease.

Investigational Therapies Miss Primary End Point in Alzheimer Disease Trial

By

Steve Duffy

Topline data were announced from the phase 2/3 DIAN-TU study of solanezumab (Eli Lilly) and gantenerumab (Genentech) in patients at risk for or with dominantly inherited Alzheimer disease.

Belsomra Labeling Updated to Include Data on Insomnia in Alzheimer Disease

By

Brian Park, PharmD

The Food and Drug Administration (FDA) has approved updates to the prescribing information for Belsomra® (suvorexant; Merck) to include study findings for the treatment of insomnia in patients with mild to moderate Alzheimer disease.

Antipsychotic Initiation Raises Risk for Head Injury, TBI in Alzheimer Disease

Individuals with Alzheimer disease (AD) initiating antipsychotics have an increased risk for head injuries and traumatic brain injury.

Decrease in US Incidence of Alzheimer Disease Seen From 2007 to 2014

From 2007 to 2014, there was a decrease in the diagnosed incidence of Alzheimer disease.

Early-Stage Alzheimer Disease Has Adverse Financial Consequences

Robust evidence shows households are at significant risk for large adverse changes in liquid assets.