Alzheimer Disease and Dementia

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Racial Differences Identified in Some Biomarkers of Alzheimer Disease

Differences in Alzheimer biomarkers suggest possible race-dependent biological mechanisms that contribute to expression of disease.

Physical Frailty Associated With Symptoms of Dementia, Caregiver Burden in Alzheimer Disease

By

Emily Pond

Per study data published in the Journal of Clinical Psychiatry, investigators hypothesized that the correlation between higher Frailty Index scores and increased caregiver burden was partially mediated by increased behavioral and psychological symptoms of dementia.

Trazodone: Not Safer Than Atypical Antipsychotics in Patients With Dementia

By

Laurel Ranger

The use of trazodone in older patients with dementia was associated with similar levels of risk for falls and fractures as atypical antipsychotics.

Prevalence of Alzheimer Disease, Related Dementia Set to Double

The burden of Alzheimer disease and related dementias (ADRD) is expected to increase to 3.3% in the United States by 2060.

Apathy Associated With Increased Risk for Dementia

By

Abigail Nover

These findings have high clinical relevance because patients with apathy are likely to withdraw from care.

Increased Levels of Human Herpesvirus Identified in Alzheimer Disease

Participants with Alzheimer disease have increased levels of 2 strains of human herpesvirus.

Sugary Drinks, Other Added Sugars May Up Risk for Alzheimer Disease

By

DaHee Han, PharmD

Drinking sugary beverages has been previously linked to markers of preclinical Alzheimer disease, but the risk associated with consuming added sugars is not established.

Cannabinoid Shows Promise for Reducing Agitation, Aggression in Alzheimer Disease

By

DaHee Han, PharmD

Although treatment with nabilone significantly improved agitation, cognition, and nutrition, the authors cautioned that sedation should be closely monitored.

Diclofenac Use Slows Cognitive Decline in Alzheimer Disease

By

Psychiatry Advisor Content Writers

Results showed that most common NSAIDs, including aspirin, ibuprofen, naproxen, and celecoxib, did not alter cognitive degeneration in patients with mild cognitive impairment or Alzheimer disease.

Some Statins May Be Associated With Cognition, Memory Deficits

By

DaHee Han, PharmD

Given the lack of differences seen via the NIS, the authors suggested that subjective questionnaires may not be a trustworthy method to assess possible statin-associated cognitive deficits.