Alzheimer Disease and Dementia

Latest News

“Morning People” at Higher Risk of Alzheimer Disease

By

Heather R. Johnson

The comorbidity of depressive disorders and late-life neurodegenerative diseases including Alzheimer disease has been widely reported. This study looks into whether there is a causal relationship existing between both or, if their co-occurrence is due to confounding or common risk factors, such as aging.

Apathy in Older Adults May Signal Risk for Developing Dementia

Apathy is associated with an increased risk for developing probable dementia for community-dwelling older adults.

The Brain Age Index Calculated From Sleep Polysomnograms Detects Deviations From Healthy Brain Aging

By

Jessica Nye, PhD

Study findings suggest that the brain age index may be an effective biomarker associated with dementia. It could also be used as a screening tool for the presence of underlying neurodegenerative disease and for the monitoring of disease progression.

Alcohol-Induced Loss of Consciousness Associated With Dementia

By

Rose Reeb

Examining the risk of future dementia associated with overall alcohol consumption andalcohol-induced loss of consciousness amongst current drinkers.

Literature Review Explores Potential Neuroprotective Effects of Resveratrol

By

Emily Pond

The eligibility criteria of the studies include: a maximum of 10 years having passed from the study publication, geographical diversity of the studies performed, and results pertaining both to animal models of AD, and to humans.

Individuals With a High Genetic Risk for Alzheimer’s Disease Have Altered Sleep Patterns

By

Jessica Nye, PhD

Is there a causal relationship between depressive disorders and late-life neurodegenerative diseases? Or, is their co-occurrence due to confounding or common risk factors, such as aging?

Feeling Dizzy Upon Standing May Point to Later Dementia

Systolic orthostatic hypotension and variability in visit-to-visit seated systolic blood pressure postural change are associated with greater dementia risk.

Cerebrovascular Reactivity Predicts Cognitive Impairment Independent of AD

By

Amit Akirov, MD

MRI-based cerebrovascular reactivity is associated with cognitive function independent of Alzheimer disease pathology.

Aducanumab Gets Priority Review for Alzheimer Disease

By

Diana Ernst, RPh

The FDA has accepted for Priority Review the Biologics License Application for aducanumab (Biogen) for the treatment of Alzheimer disease.

Education May Affect β-Amyloid Burden in Alzheimer Disease

Years of education and the ε4 risk allele at APOE influence β-amyloid pathology in asymptomatic individuals with a parental history of sporadic Alzheimer disease, while only years of education influence β-amyloid pathology in presymptomatic autosomal dominant AD mutation carriers.