Alzheimer Disease and Dementia

Latest News

Prevalence of Risk Factors for Alzheimer, Related Dementias Identified

The prevalence of risk factors for ADRD varies and is highest for high BP and not meeting aerobic physical activity guidelines.

Type I Interferon (IFN-I) Signaling Critical Component of Neuroinflammatory Network in Alzheimer Disease

By

Jessica Nye, PhD

Investigators at Baylor College of Medicine used a murine model (5XFAD) to evaluate brain-wide cellular reactions to IFN-I and its potential role in cognition and neuropathy.

Age-Specific Dementia Risk Scores Developed for Mid, Late Life

Age-specific dementia risk scores should prioritize different risk factors in mid and late life.

Childhood Trauma Associated With Dementia Symptoms in Former Football Players

By

Mary Stroka

Researchers sought to determine whether concussions and a history of playing football influenced a possible association between ACEs and poor neuropsychiatric health.

Immunotherapeutic Vaccine Candidate Fast Tracked for Alzheimer Disease

By

Brian Park, PharmD

UB-311 is an immunotherapeutic vaccine candidate that targets toxic forms of aggregated amyloid beta in the brain.

Sleep Disturbances in Alzheimer Disease Tied to Loss of ‘Wakeful’ Neuron

By

Jessica Nye

Researchers sought to examine the association between the number of important subcortical wake-promoting neurons and clinical sleep phenotypes in patients with AD or PSP.

Obesity, Physical Inactivity, Low Education Associated With ADRD Cases

Midlife obesity, physical inactivity, and low education are the three most prominent modifiable risk factors associated with ADRDs.

Medicare Policy Changes Reduce Hospice Use for Dementia

Medicare policies are associated with reductions in the share of patients with an Alzheimer disease and related dementias code receiving hospice care.

Antioxidants Are Associated With Reduced Risk of All-Cause Dementia

Antioxidants such as serum level of lutein+zeaxanthin and β-cryptoxanthin are associated with a reduced risk for all-cause dementia.

Interventions for Men, Women With Alzheimer Disease Improve Cognition

Multidomain interventions are equally effective for improving cognition in women and men.