While sleep dysregulation is a feature of dementia, it remains unclear whether the duration of sleep prior to old age is associated with dementia. The researchers examined the association between sleep duration and incidence of dementia using a 25-year follow-up.
In addition, steeper decline in eGFR within one year associated with higher dementia risk
The study researchers used deep whole-genome sequencing (WGS) to search for novel AD variants in 2247 individuals from 605 multiplex AD families from the National Institute on Mental Health and the National Institute on Aging (NIA) Alzheimer’s Disease Sequencing Project `data sets.
Younger age at onset of type 2 diabetes is associated with an increased risk for subsequent dementia.
Researchers evaluated a case study of a patient who was diagnosed with frontotemporal behavioral dementia whose autopsy showed coexistent TDP-43 type A and Alzheimer disease pathologies and cerebrovascular disease.
There may be an association between a history of psychiatric disorders in patients and age of onset of Alzheimer disease.
Evidence suggests the importance of decreasing -amyloid deposition in brains of patients with Alzheimer disease early in care.
Patients with Lewy body dementia with likely AD-type copathology may have impaired language compared to those without such copathology.
Persistent loneliness in midlife is associated with a higher risk of Alzheimer disease (AD) and other dementias. The good news is that people who bounce back from loneliness build resilience to dementia and AD.
Study researchers sought to assess the racial differences in triggering receptor expressed on myeloid cells 2 in patients with Alzheimer disease.