Differences in Alzheimer biomarkers suggest possible race-dependent biological mechanisms that contribute to expression of disease.
Per study data published in the Journal of Clinical Psychiatry, investigators hypothesized that the correlation between higher Frailty Index scores and increased caregiver burden was partially mediated by increased behavioral and psychological symptoms of dementia.
The use of trazodone in older patients with dementia was associated with similar levels of risk for falls and fractures as atypical antipsychotics.
The burden of Alzheimer disease and related dementias (ADRD) is expected to increase to 3.3% in the United States by 2060.
These findings have high clinical relevance because patients with apathy are likely to withdraw from care.
Participants with Alzheimer disease have increased levels of 2 strains of human herpesvirus.
Drinking sugary beverages has been previously linked to markers of preclinical Alzheimer disease, but the risk associated with consuming added sugars is not established.
Although treatment with nabilone significantly improved agitation, cognition, and nutrition, the authors cautioned that sedation should be closely monitored.
Results showed that most common NSAIDs, including aspirin, ibuprofen, naproxen, and celecoxib, did not alter cognitive degeneration in patients with mild cognitive impairment or Alzheimer disease.
Given the lack of differences seen via the NIS, the authors suggested that subjective questionnaires may not be a trustworthy method to assess possible statin-associated cognitive deficits.