SSRI Antidepressants Exacerbate Rapid Cycling in Bipolar Disorder

Long-term continuation of SSRI antidepressants in people with rapid cycling led to more mood and depressive episodes.

SSRI antidepressants are linked to deteriorating emotional rapid cycling in patients suffering from bipolar disorder, researchers suggest.

According to study published in the Journal of Affective Disorders, psychiatric researchers initiated a randomized study to further certify the “lack of safety” that antidepressants may have on a huge portion of people with bipolar disorder.

Researchers from the University of Louisville, Tufts, Stanford, and the University of Pennsylvania, performed a secondary analysis of the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD), to better understand the relationship betweenrapid cycling and antidepressants.

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