Schizophrenia, depression, and bipolar disorder have more in common than previously thought. Not only are they linked through shared genes, the genetic mutations associated with them also work together to govern immunity, brain signaling, and genome function later in life, according to a Nature Neuroscience study. The new finding may mean that only one drug will be required to treat all these disorders in the future.
This is the first study to show the genetic overlap between psychiatric disorders leads to meaningful paths for treatment, says Peter Holmans, a biostatistician at King’s College London and a co-author the study. Essentially, it translates the genetic information into a roadmap for drug discovery.
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