Genetics’ Role in Association Between Depression and Back Pain

Genetic factors help to explain the commonly found association between low back pain and depression, suggests a large study of twins in the March issue of Pain, the official publication of the International Association for the Study of Pain.

Genetic factors affecting both conditions may be involved in the association between back pain and depression, according to the report by Marina B. Pinheiro, MSc, and colleagues of The University of Sydney, Australia, and Murcia Twin Registry, Spain.

The researchers analyzed data from an established database (Murcia Twin Registry) of nearly 2,150 Spanish twins. Twin studies provide a unique opportunity to elucidate the association between health conditions, by eliminating the genetic and environmental factors contributing to them. 

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