Depressive Disorder

Features

Pharmacogenetic Testing: Does it Improve Therapy in Patients With MDD?

By

Lauren Nolan, MMSc, PA-C

Tia M. Solh, MT (ASCP), MSPAS, PA-C

Testing for genetic variants may allow clinicians to predict how patients with major depressive disorder metabolize antidepressants.

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Comparing the Quality of Life in Parkinson Disease Patients With Subthreshold Depression vs Patients With No Depressive Disorder

By

Heather R. Johnson

Subthreshold depression was found to be a problem with Parkinson Disease patients. Quality of life is worse and non-motor symptoms burden is greater.

Staying on Antidepressants During Pregnancy Increases Risk of Obstetric Complications, Postpartum Psychiatric Disorders

By

Brandon May

Women who stopped antidepressant treatment during pregnancy and resumed in the following weeks had a rebound effect of increased prescription of benzodiazepines and anxiolytics.

Acne and Mental Health

By

Emily Pond

Acne’s association with low self-esteem, stress, anxiety, and depression and their affects, are explored.

Emotional Memory Retrieval Prior to Electroconvulsive Therapy in Patients With Major Depressive Disorder

By

Sheila Jacobs

Can emotional memory retrieval just prior to electroconvulsive therapy sessions improve the outcome of ECT in patients with major depressive disorder?

SSRI Use Resolves Depression, Increases Recurrent Stroke Risk After ICH

By

Heather R. Johnson

SSRI use after intracerebral hemorrhage may resolve depression symptoms, but also increases patients’ risk for recurrent stroke.

Depressive Symptoms in Peripheral Artery Disease May Be Associated With Poorer Health Status

By

Brandon May

A substantial percentage of women with peripheral artery disease reported having depressive symptoms.

mRNA Expression Signatures for Identifying Response to Antidepressant Therapies

By

Sheila Jacobs

Investigators examined the mRNA signature foundation associated with the pro-inflammatory phenotype of depression, along with the differential signatures linked to depression subtypes and the impact of antidepressant agents.

COVID-19: Physical Activity May Improve Well-Being During Quarantine

By

Heather R. Johnson

This study is the first quantitative verification of a link between engagement in physical activity and resilience, positive affect, and depressive symptoms in older adults within COVID-19 restrictions.

Individuals With a High Genetic Risk for Alzheimer’s Disease Have Altered Sleep Patterns

By

Jessica Nye, PhD

Is there a causal relationship between depressive disorders and late-life neurodegenerative diseases? Or, is their co-occurrence due to confounding or common risk factors, such as aging?

Study Identifies Characteristics of Depression Care in Primary Care Clinics

By

Emily Pond

Depression, a significant cause of disability in the United States, is largely managed by primary care providers; therefore, understanding how these clinicians manage depression is an important step toward identifying opportunities for improvement.