For the first time, scientists have discovered that braininflammation caused by chronic nerve pain can affect signaling in theregions of the brain associated with mood and motivation. This discoverysuggests there is a mechanism that connects chronic pain with symptomsof depression and anxiety that many patients experience.

The findings of the study, published in the Journal of Neuroscience,could lead to new methods of treatment for chronic pain, the mostcommon form of enduring illness for people aged below 60 in the US.

Researchers from the University of California-Irvine(UCI) and theUniversity of California-Los Angeles (UCLA) made their discovery afterexamining the growth of immune cells in the brains of mice and rats withchronic pain.

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