Rates of depression in women in perimenopause — the period leading up to menopause, roughly between 41 and 51 years of age — are unusually high. He says he got the idea to study the potential role of MAO-A in perimenopause depression because of clinical work he does at the centre. And that too is associated with high levels of MAO-A in the prefrontal cortex, the front of the brain.

READ FULL ARTICLE Curated publisher From Toronto Star