Brain Protein May Cause High Depression Rates in Perimenopause

Brain protein may be cause of high rates of depression in perimenopause
Brain protein may be cause of high rates of depression in perimenopause
Levels of MAO-A in the brain are known to rise as levels of estrogen drop.

Rates of depression in women in perimenopause — the period leading up to menopause, roughly between 41 and 51 years of age — are unusually high. He says he got the idea to study the potential role of MAO-A in perimenopause depression because of clinical work he does at the centre. And that too is associated with high levels of MAO-A in the prefrontal cortex, the front of the brain.

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