Objectively measured cognition in patients with bipolar disorder was directly associated with performance-based functional capacity, but not with interview-based or self-reported functional capacity.
Mood stabilizers and second-generation antipsychotics are associated with a high incidence of failure in bipolar disorder during the first year of treatment.
Worse outcomes are associated with comorbid attention-deficit/hyperactivity disorder and bipolar disorder, but cognitive testing has limited differential value in identifying this group.
Tobacco use, either on its own or coupled with alcohol use disorder or cannabis use disorder, was a significant risk factor for recurrent suicide attempts in individuals with bipolar disorder.
Youth who are readmitted for inpatient psychiatric care share such factors as foster care, comorbid conditions, and prior psychiatric hospitalizations.
Genetic liability for major depression increases the risk for suicide attempts in major depressive disorder, bipolar disorder, and schizophrenia.
Aripiprazole augmentation to lithium carbonate seemed to be the best option in treatment-resistant patients with comorbid bipolar disorder and obsessive-compulsive disorder.
Patients with obsessive-compulsive disorder and bipolar disorder are at greater risk for suicide.
Women have slightly longer inpatient hospitalizations for bipolar disorder-related symptoms, although factors such as psychotropic treatment and comorbid personality disorders mitigate the results.
Hyperthymic and cyclothymic temperaments and an elevated number of recent life events were associated with both patients with bipolar disorder and their healthy siblings.