The key findings of the study, conducted in the world’s largest BD cohort with genotypic and phenotypic data, offer potential sleep-related genetic underpinnings for BD diagnostic groups.
For both patients with ulcerative colitis and those with Crohn disease, psychiatric diagnoses were more common in those who were elderly (greater than 65 years old), women, and white, and those with psychiatric conditions more frequently had a history of alcohol abuse, tobacco and substance abuse, personality disorder, and corticosteroid use.
Published studies that included data on the risk for PD in patients with BD vs the general population without BD were included in a systematic review.
Researchers found a weak signal for persistent ADHD to be more associated with 8-year follow-up of bipolar disorder than remitting ADHD.
Researchers conducted a retrospective review to assess the clinical and demographic characteristics of patients with and without rapid cycling in bipolar disorder.
Researchers assessed the total effect of bipolar disorder and major depression on cognitive function in adults between 40 and 69 years old and measured the effects mediated by psychotropic drug use and cardiometabolic disease.
Investigators compared antibodies to common infectious agents, including cytomegalovirus, Toxoplasma gondii, and measles, as well as the inflammatory marker C-reactive protein, in serum samples in patients with bipolar disorder vs control participants without bipolar disorder.
Investigators analyzed the potential metabolic effects of lurasidone in a sample of patients with bipolar I depression.
Compared with olanzapine and aripiprazole, lurasidone was linked with lower risk for all-cause and psychiatric hospitalization in pediatric patients.
Lithium use was associated with lower intensity of depressive symptoms, reduced clinical severity, and lower benzodiazepine use.